Towards A Novel Multi-Epitopes Chimeric Vaccine for Simulating Strong Immune Responses and Protection against Morganella morganii

A Ullah, S Ahmad, S Ismail, Z Afsheen… - International Journal of …, 2021 - mdpi.com
Morganella morganii is one of the main etiological agents of hospital-acquired infections
and no licensed vaccine is available against the pathogen. Herein, we designed a multi …

Electrolyte structure near electrodes with molecular-size roughness

T Aslyamov, K Sinkov, I Akhatov - Physical Review E, 2021 - APS
Understanding electrodes' surface morphology influence on ions' distribution is essential for
designing supercapacitors with enhanced energy density characteristics. We develop a …

A Study on the Binding Mechanism and the Impact of Key Residue Mutations between SND1 and MTDH Peptide through Molecular Dynamics Simulations

S Liu, X Hao, D Miao, Y Zhang - The Journal of Physical Chemistry …, 2024 - ACS Publications
Metastasis of breast cancer is the main cause of death for patients with breast cancer. The
interaction between metadherin (MTDH) and staphylococcal nuclease domain 1 (SND1) …

Exploration of the product specificity of chitosanase CsnMY002 and mutants using molecular dynamics simulations

J Lu, C Wang, Y Ma, K Liu, X Fu, S Xing - Molecules, 2023 - mdpi.com
Chitosanase CsnMY002 is a new type of enzyme isolated from Bacillus subtilis that is used
to prepare chitosan oligosaccharide. Although mutants G21R and G21K could increase …

Exploring binding modes of the selected inhibitors to SND1 by all-atom molecular dynamics simulations

P Pang, S Liu, X Hao, Y Tian, S Gong… - Journal of …, 2024 - Taylor & Francis
Breast cancer is the leading cause of cancer-related deaths in women. Previous studies
have indicated that disrupting the interaction between Metadherin (MTDH) and …

Revealing the binding mechanism of BACE1 inhibitors through molecular dynamics simulations

Y Zhang, D Miao, S Liu, X Hao - Journal of Biomolecular Structure …, 2024 - Taylor & Francis
Alzheimer's disease is a debilitating neurodegenerative disorder, and the Beta-Site Amyloid
Precursor Protein Cleaving Enzyme 1 (BACE1) is a key therapeutic target in its treatment …

Application of Mayer's activity expansions to the Ising problem

MV Ushcats, LA Bulavin, SY Ushcats… - Physica A: Statistical …, 2022 - Elsevier
Recent successes in approximate evaluations of high-order cluster integrals have greatly
advanced the quantitative applicability of Mayer's cluster expansion for various statistical …

Construction of subcritical isotherms for model and real gases on the basis of Mayer's cluster expansion

MV Ushcats, LA Bulavin - Physical Review E, 2020 - APS
Existing rigorous statistical approaches still cannot quantitatively describe condensation
phenomena in real fluids and even model systems with some simplified interaction potential …

A method to approximate cluster integrals and reproduce subcritical isotherms for model and real gases

MV Ushcats, LA Bulavin - arXiv preprint arXiv:2003.02217, 2020 - arxiv.org
A method is proposed to approximate the unlimited subcritical set of Mayers reducible
cluster integrals (ie, the power coefficients of the known virial expansions for pressure and …