Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …

Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …

Neural recordings using invasive devices in humans can elucidate the circuits underlying
brain disorders, but have so far been limited to short recordings from externalized brain …

Objective. Contemporary deep brain stimulation (DBS) for Parkinson's disease is delivered
continuously, and adjustments based on patient's changing symptoms must be made …

The ability to dynamically change motor outputs, such as stopping an initiated response, is
an important aspect of human behavior. A hyperdirect pathway between the inferior frontal …

Deep brain stimulation (DBS) is an approved therapy for the treatment of medically refractory
and severe movement disorders. However, most existing neurostimulators can only apply …

Oscillations in neural activity play a critical role in neural computation and communication.
There is intriguing new evidence that the nonsinusoidal features of the oscillatory waveforms …

A monosynaptic projection from the cortex to the subthalamic nucleus is thought to have an
important role in basal ganglia function and in the mechanism of therapeutic subthalamic …

This review is part of the series on the clinical neurophysiology of movement disorders. It
focuses on Parkinson's disease and parkinsonism. The topics covered include the …

OBJECTIVE Dysfunction of distributed neural networks underlies many brain disorders. The
development of neuromodulation therapies depends on a better understanding of these …