Small molecule metabolites: discovery of biomarkers and therapeutic targets

S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

[HTML][HTML] The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions

M Trøseid, GØ Andersen, K Broch, JR Hov - EBioMedicine, 2020 - thelancet.com
Host-microbiota interactions involving inflammatory and metabolic pathways have been
linked to the pathogenesis of multiple immune-mediated diseases and metabolic conditions …

Remodeling of the gut microbiome by Lactobacillus johnsonii alleviates the development of acute myocardial infarction

X Zhong, Y Zhao, L Huang, J Liu, K Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction The gut microbial community, which can be disturbed or repaired by changes in
the internal environment, contributes to the development of acute myocardial infarction …

Gut microbiome mediates the protective effects of exercise after myocardial infarction

Q Zhou, J Deng, X Pan, D Meng, Y Zhu, Y Bai, C Shi… - Microbiome, 2022 - Springer
Background Gut microbiota plays important roles in health maintenance and diseases.
Physical exercise has been demonstrated to be able to modulate gut microbiota. However …

Inflammatory response: a crucial way for gut microbes to regulate cardiovascular diseases

W Wang, LJ Zhu, YQ Leng, YW Wang, T Shi, WZ Wang… - Nutrients, 2023 - mdpi.com
Gut microbiota is the largest and most complex microflora in the human body, which plays a
crucial role in human health and disease. Over the past 20 years, the bidirectional …

Pharmacological modulation of cardiac remodeling after myocardial infarction

W Zhao, J Zhao, J Rong - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
Cardiac remodeling describes a series of structural and functional changes in the heart after
myocardial infarction (MI). Adverse post‐MI cardiac remodeling directly jeopardizes the …

Exosomes derived from human placental mesenchymal stem cells ameliorate myocardial infarction via anti-inflammation and restoring gut dysbiosis

L Yang, T Wang, X Zhang, H Zhang, N Yan… - BMC cardiovascular …, 2022 - Springer
Background Myocardial infarction (MI) represents a severe cardiovascular disease with
limited therapeutic agents. This study was aimed to elucidate the role of the exosomes …

[HTML][HTML] Protective effect of Lactobacillus rhamnosus GG and its supernatant against myocardial dysfunction in obese mice exposed to intermittent hypoxia is …

H Xu, J Wang, J Cai, W Feng, Y Wang… - International Journal of …, 2019 - ncbi.nlm.nih.gov
Prolonged intermittent hypoxia (IH) has been shown to impair myocardial function (mainly
via oxidative stress and inflammation) and modify gut microbiota in mice. Gut microbiota …

The role of gut microbiota in heart failure: when friends become enemies

R Cianci, L Franza, R Borriello, D Pagliari, A Gasbarrini… - Biomedicines, 2022 - mdpi.com
Heart failure is a complex health issue, with important consequences on the overall
wellbeing of patients. It can occur both in acute and chronic forms and, in the latter, the …

Electroacupuncture interventions alleviates myocardial ischemia reperfusion injury through regulating gut microbiota in rats

H Bai, RJ Gu, LY Chen, Y Qian, ML Yu, SL Xu… - Microvascular …, 2021 - Elsevier
Electroacupuncture (EA) intervention has a remarkable cardioprotection against myocardial
ischemia reperfusion injury (MIRI). Recently, it has been suggested that the gut microbiota …