SUMMARY A defining characteristic of eukaryotic cells is the possession of a nuclear
envelope. Transport of macromolecules between the nuclear and cytoplasmic compartments …

In eukaryotes, the separation of translation from transcription by the nuclear envelope
enables mRNA modifications such as capping, splicing, and polyadenylation. These …

Yra1p, a conserved nuclear RNA‐binding protein, interacts directly with Mex67p and is required
for mRNA export | The EMBO Journal All EMBO Press journals Open Access as of 1 January …

The yeast nuclear protein Yra1p is an essential export factor for mRNA. Yra1p interacts
directly with the mRNA transport factor Mex67p/Mtr2p, which is associated with the nuclear …

The nuclear envelope is a physical barrier between the nucleus and cytoplasm and, as
such, separates the mechanisms of transcription from translation. This compartmentalization …

Yra1p and Sub2p are components of the TREX complex, which couples transcription
elongation with nuclear export of mRNAs. Here, we report a genetic interaction between …

In eukaryotic cells, nuclear export of nascent ribosomal subunits through the nuclear pore
complex depends on the small GTPase Ran. However, neither the nuclear export signals …

The study of the dynamic interactome of cellular ribonucleoprotein (RNP) particles has been
hampered by severe methodological limitations. In particular, the affinity purification of intact …

It is not known how Mex67p and Mtr2p, which form a heterodimer essential for mRNA export,
transport mRNPs through the nuclear pore. Here, we show that the Mex67p/Mtr2p complex …

Oxidative stress is known to affect both translation and protein turnover, but very few large
scale studies describe protein expression under stress. We measure protein concentrations …