Immune-mediated hepatitis induced by immune checkpoint inhibitors: Current updates and future perspectives

Z Liu, Y Zhu, H Xie, Z Zou - Frontiers in Pharmacology, 2023 - frontiersin.org
In recent years, cancer immunotherapy has made remarkable achievements. Immune
checkpoint inhibitors (ICIs) have been used successfully in several types of cancer in the …

The predictive potential of the baseline C-reactive protein levels for the efficiency of immune checkpoint inhibitors in cancer patients: a systematic review and meta …

CL Han, GX Meng, ZN Ding, ZR Dong… - Frontiers in …, 2022 - frontiersin.org
Background The relationship between baseline C-reactive protein (CRP) level and the
prognosis of cancer patients receiving immune checkpoint inhibitor (ICI) treatment remains …

Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination

EB Ellingsen, G Bounova, I Kerzeli, I Anzar… - Journal of translational …, 2022 - Springer
Background This clinical trial evaluated a novel telomerase-targeting therapeutic cancer
vaccine, UV1, in combination with ipilimumab, in patients with metastatic melanoma …

[HTML][HTML] The future of targeted kinase inhibitors in melanoma

S Caksa, U Baqai, AE Aplin - Pharmacology & therapeutics, 2022 - Elsevier
Melanoma is a cancer of the pigment-producing cells of the body and its incidence is rising.
Targeted inhibitors that act against kinases in the MAPK pathway are approved for BRAF …

Incidence of Cutaneous Immune-Related Adverse Events and Outcomes in Immune Checkpoint Inhibitor-Containing Regimens: A Systematic Review and Meta …

NB Curkovic, K Bai, F Ye, DB Johnson - Cancers, 2024 - mdpi.com
Simple Summary Immune checkpoint inhibitors are increasingly being used in the treatment
of a variety of cancers, both alone and in combination with other cancer therapies. Side …

Immune checkpoint inhibitor-induced liver injury

CLC Gudd, R Sheth, MR Thursz… - Seminars in Liver …, 2023 - thieme-connect.com
In recent years cancer treatment has been revolutionized by the development and wide
application of checkpoint inhibitor (CPI) drugs, which are a form of immunotherapy. CPI …

Assessment of Variables Related to the Risk of Severe Adverse Events in Cutaneous Melanoma Patients Treated with Immune Checkpoint Inhibitors

KP Trichkova, F Görtler, L Bjørge, C Schuster - Cancers, 2024 - mdpi.com
Simple Summary Malignant melanoma is an aggressive cancer with a globally increasing
disease rate. Historically, overall survival has been less than one year for advanced disease …

Hepatitis-related adverse events associated with immune checkpoint inhibitors in cancer patients: an observational, retrospective, pharmacovigilance study using the …

Z Fu, J Liu, C Zhang, H Hu, S Li, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Background: Immune checkpoint inhibitors (ICIs), including anti-PD-1, anti-PD-L1 and anti-
CTLA-4 antibodies, have become a standard treatment for multiple cancer types. However …

The relationship between LDH and GLIM criteria for cancer cachexia: Systematic Review and Meta-Analysis.

J Thompson, J McGovern, C Roxburgh… - Critical Reviews in …, 2024 - Elsevier
Introduction Cancer cachexia is a clinical condition characterized by recognizable “sickness
behaviors” accompanied by loss of lean body tissue. The Global Leadership on Malnutrition …

Recent advances in immunotherapy and its combination therapies for advanced melanoma: A review

J Xu, S Mu, Y Wang, S Yu, Z Wang - Frontiers in Oncology, 2024 - pmc.ncbi.nlm.nih.gov
The incidence of melanoma is increasing year by year and is highly malignant, with a poor
prognosis. Its treatment has always attracted much attention. Among the more clinically …