Endothelial activation and dysfunction is an important contributor to atherosclerosis,
cardiovascular diseases and cardiorenal syndrome. Endothelial dysfunction is also linked …

Epidemiological studies established that elevated homocysteine, an important intermediate
in folate, vitamin B12, and one carbon metabolism, is associated with poor health, including …

The endothelium exerts multiple actions involving regulation of vascular permeability and
tone, coagulation and fibrinolysis, inflammatory and immunological reactions and cell …

Homocysteine (Hcy) is an intermediate amino acid formed during the conversion from
methionine to cysteine. When the fasting plasma Hcy level is higher than 15 μmol/L, it is …

Homocysteine, an amino acid containing a sulfhydryl group, is an intermediate product
during metabolism of the amino acids methionine and cysteine. Hyperhomocysteinemia is …

Dysregulation of one-carbon metabolism affects a wide range of biological processes and is
associated with a number of diseases, including cardiovascular disease, dementia, neural …

Objective—We aimed to examine whether baseline homocysteine (Hcy) concentrations
affect antihypertensive responses to enalapril treatment among previously untreated …

Abstract During pregnancy, estrogen (E 2) stimulates uterine artery blood flow (UBF) by
enhancing nitric oxide (NO)-dependent vasodilation. Cystathionine γ-lyase (CSE) promotes …

Although it is known that 1-methylnicotinamide (MNA) displays vasoprotective activity in
mice, as yet the effect of MNA on endothelial function has not been demonstrated in vivo …

Over the last decade, increasing research has focused on urinary exosomes (UEs) in
biological fluids and their relationship with physiological and pathological processes. UEs …