Nanoparticles in drug delivery: From history to therapeutic applications

O Afzal, ASA Altamimi, MS Nadeem, SI Alzarea… - Nanomaterials, 2022 - mdpi.com
Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …

Nanoparticles: alternatives against drug-resistant pathogenic microbes

GR Rudramurthy, MK Swamy, UR Sinniah… - Molecules, 2016 - mdpi.com
Antimicrobial substances may be synthetic, semisynthetic, or of natural origin (ie, from plants
and animals). Antimicrobials are considered “miracle drugs” and can determine if an …

Effects of particle size and surface modification on cellular uptake and biodistribution of polymeric nanoparticles for drug delivery

SA Kulkarni, SS Feng - Pharmaceutical research, 2013 - Springer
Purpose To investigate the effects of the particle size and surface coating on the cellular
uptake of the polymeric nanoparticles for drug delivery across the physiological drug barrier …

PLGA-based nanoparticles as cancer drug delivery systems

FS Tabatabaei Mirakabad, K Nejati-Koshki… - Asian Pacific Journal …, 2014 - koreascience.kr
Poly (lactic-co-glycolic acid)(PLGA) is one of the most effective biodegradable polymeric
nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems …

Biodegradable nanoparticles for drug and gene delivery to cells and tissue

J Panyam, V Labhasetwar - Advanced drug delivery reviews, 2003 - Elsevier
Biodegradable nanoparticles formulated from poly (d, l-lactide-co-glycolide)(PLGA) have
been extensively investigated for sustained and targeted/localized delivery of different …

Nanoparticles and controlled delivery for bioactive compounds: Outlining challenges for new “smart-foods” for health

MC Martínez-Ballesta, Á Gil-Izquierdo… - Foods, 2018 - mdpi.com
Nanotechnology is a field of research that has been stressed as a very valuable approach
for the prevention and treatment of different human health disorders. This has been stressed …

Nanoparticle-mediated drug delivery for the treatment of cardiovascular diseases

R Pala, VT Anju, M Dyavaiah, S Busi… - International journal of …, 2020 - Taylor & Francis
Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and
mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are …

Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines

A Mahapatro, DK Singh - Journal of nanobiotechnology, 2011 - Springer
Biodegradable nanoparticles (NPs) are gaining increased attention for their ability to serve
as a viable carrier for site specific delivery of vaccines, genes, drugs and other biomolecules …

A novel controlled release formulation for the anticancer drug paclitaxel (Taxol®): PLGA nanoparticles containing vitamin E TPGS

L Mu, SS Feng - Journal of controlled release, 2003 - Elsevier
Paclitaxel (Taxol®) is one of the best antineoplastic drugs found from nature in the past
decades. Like many other anticancer drugs, there are difficulties in its clinical administration …

[PDF][PDF] Nano and microparticles as controlled drug delivery devices

M Kumar - J. Pharm. Pharm. Sci, 2000 - ualberta.ca
Although, the drug delivery system (DDS) concept is not new, great progress has recently
been made in the treatment of a variety of diseases. Targeting delivery of drugs to the …