Resistome expansion in disease-associated human gut microbiomes

S Fredriksen, S de Warle, P van Baarlen, J Boekhorst… - Microbiome, 2023 - Springer
Background The resistome, the collection of antibiotic resistance genes (ARGs) in a
microbiome, is increasingly recognised as relevant to the development of clinically relevant …

Subchronic oral cylindrospermopsin exposure alters the host gut microbiome and is associated with progressive hepatic inflammation, stellate cell activation, and mild …

P Saha, M Upright, D Bose, S Roy, A Trivedi, M More… - Toxins, 2022 - mdpi.com
Epidemiological studies have reported a strong association between liver injury and
incidences of hepatocellular carcinoma in sections of humans globally. Several preclinical …

Double-edged sword: impact of fecal microbiome transplants on the gut resistome

HA Hallowell, AL Gao, J Suez - Current opinion in …, 2023 - journals.lww.com
Research on resistome modulation by FMT is preliminary, and human studies currently lack
consensus regarding benefits and risks. From a safety perspective, screening donor …

Microbiome dysbiosis shows strong Association of gut-Derived Altered Metabolomic Profile in gulf war chronic multisymptom illness symptom persistence following …

D Bose, V Stebliankin, T Cickovski, P Saha… - International journal of …, 2023 - mdpi.com
The pathophysiology of Gulf War Illness (GWI) remains elusive even after three decades.
The persistence of multiple complex symptoms along with metabolic disorders such as …

A Double-Humanized Mouse Model for Studying Host Gut Microbiome–Immune Interactions in Gulf War Illness

D Bose, P Saha, S Roy, A Trivedi, M More… - International Journal of …, 2024 - mdpi.com
Unraveling the multisymptomatic Gulf War Illness (GWI) pathology and finding an effective
cure have eluded researchers for decades. The chronic symptom persistence and limitations …

Unraveling the Genomic Crosstalk of Host Microbiome in Human and Humanized Preclinical Models of Gulf War Illness

D Bose - 2024 - search.proquest.com
Understanding the complex pathology of Gulf War Illness (GW), with its multisymptomatic
condition, and identifying an efficient treatment has been a longstanding challenge for …