This paper discusses the current evidence from animal and human studies for a central role
of inflammation in schizophrenia. In animal models, pre-or perinatal elicitation of the immune …

High levels of pro-inflammatory substances such as cytokines have been described in the
blood and cerebrospinal fluid of schizophrenia patients. Animal models of schizophrenia …

The neurodevelopmental model of schizophrenia, which posits that the illness is the end
state of abnormal neurodevelopmental processes that started years before the illness onset …

Magnetic resonance imaging (MRI) allows unprecedented access to the anatomy and
physiology of the developing brain without the use of ionizing radiation. Over the past two …

In this study, we investigated whether intrinsic glial dysfunction contributes to the
pathogenesis of schizophrenia (SCZ). Our approach was to establish humanized glial …

The advent of magnetic resonance imaging, which safely allows in vivo quantification of
anatomical and physiological features of the brain, has revolutionized pediatric …

When we judge an action as morally right or wrong, we rely on our capacity to infer the
actor's mental states (eg, beliefs, intentions). Here, we test the hypothesis that the right …

A suite of recent studies has reported positive genetic correlations between autism risk and
measures of mental ability. These findings indicate that alleles for autism overlap broadly …

Classical schizophrenia literature reports motor symptoms as characteristic of the disorder.
After the introduction of neuroleptic drugs, the existence of genuine motor disorders was …

Modularity is a fundamental concept in systems neuroscience, referring to the formation of
local cliques or modules of densely intra-connected nodes that are sparsely inter-connected …