Transfer RNA-derived small RNA (tsRNA) s are novel non-coding RNAs, expressed in a
variety of tissues and organs. Two subtypes of tsRNAs have been reported: tRNA-derived …

ABSTRACT tRNA-derived small RNA (tsRNA) is a novel class of non-coding RNA that is
usually produced from tRNA following endonuclease cleavage which occurs under stress …

Abstract tRNA-derived small RNAs (tsRNAs) are non-coding RNAs with diverse functions in
various diseases. Although research on tsRNAs has focused on their roles in cancer, such …

Purpose We sought to reveal the expression profiles of transfer RNA-derived small RNAs
(tsRNAs) and microRNAs (miRNAs) in the vitreous humor of patients with proliferative …

Purpose Choroidal neovascularization (CNV) is the defining feature of neovascular age-
related macular degeneration (nAMD). Gut microbiota might be deeply involved in the …

Bone-related diseases seriously affect the lives of patients and carry a heavy economic
burden on society. Treatment methods cannot meet the diverse clinical needs of affected …

Age-related macular degeneration (AMD) is a leading cause of severe vision impairment in
the aging population. However, the underlying molecular mechanism remains unclear …

Loss of glomerular podocytes is the crucial event in the progression of chronic kidney
disease (CKD). tRNA-derived fragments (tRFs), a newfangled branch of small non-coding …

Background Tissue engineering using bone mesenchymal stem cells (BMSCs)
transplantation is a promising therapeutic for bone regeneration. However, the effect of bone …

Age-related macular degeneration (AMD) is a worldwide leading cause of blindness
affecting individuals over 50 years old. The most aggressive form, wet AMD, is characterized …