Metabolic gene clusters (MGCs), physically co-localized genes participating in the same
metabolic pathway, are signature features of fungal genomes. MGCs are most often …

The genus Scedosporium, which comprises at least five clinically relevant species, ie
Scedosporium apiospermum, Scedosporium boydii, Scedosporium aurantiacum …

Fungi contain a remarkable range of metabolic pathways, sometimes encoded by gene
clusters, enabling them to digest most organic matter and synthesize an array of potent small …

The Penicillia are known to produce a wide range natural products—some with devastating
outcome for the agricultural industry and others with unexploited potential in different …

Background Lasiodiplodia theobromae is a fungus of the Botryosphaeriaceae that causes
grapevine vascular disease, especially in regions with hot climates. Fungi in this group often …

Comparative genomic studies of microorganisms have disrupted the paradigm of vertical
inheritance with modification. First in bacteria, and more recently in microscopic and even …

Metabolic gene clusters (MGCs) have provided some of the earliest glimpses at the
biochemical machinery of yeast and filamentous fungi. MGCs encode diverse genetic …

Trichoderma is a cosmopolitan genus with diverse lifestyles and nutritional modes, including
mycotrophy, saprophytism, and endophytism. Previous research has reported greater …

Prokaryotic and eukaryotic fumarylacetoacetate hydrolase (FAH) superfamily members,
sharing conserved regions that form the so-called FAH-domain, catalyze a remarkable …

In fungi, distribution of secondary metabolite (SM) gene clusters is often associated with host-
or environment-specific benefits provided by SMs. In the plant pathogen Alternaria …