Macrophages have emerged at the forefront of research in immunology and transplantation
because of recent advances in basic science. New findings have illuminated macrophage …

Although kidney transplantation has been an important means for the treatment of patients
with end stage of renal disease, the long-term survival rate of the renal allograft remains a …

Transplant glomerulopathy is a sign of chronic kidney allograft damage. It has poor survival
and no effective therapies. This entity develops as a maladaptive repair/remodeling …

Background Transplant glomerulopathy (TG) is a diagnostic criterion for chronic active
antibody-mediated rejection (CAABMR), with C4d, donor-specific antibodies (DSA) and …

Background The presence of monocyte-macrophage lineage cells in rejecting kidney
transplants is associated with worse graft outcome. At present, it is still unclear how the …

The Clinical and Genomic Significance of Donor-Specific Anti... : Clinical Journal of the American
Society of Nephrology The Clinical and Genomic Significance of Donor-Specific …

Introduction Angiotensin II type 1 receptor antibody (AT1R-Ab), is a non–human leukocyte
antigen (HLA) antibody implicated in poor renal allograft outcomes, although its actions may …

Despite the evidences showing the relevance of regulatory immune-mediated mechanisms
to guarantee the stable graft function in renal transplanted patients, studies focusing on the …

Large numbers of macrophage lineage cells are present in transplants undergoing ischemia-
reperfusion injury and rejection, and their presence correlates with a high probability of …

In patients undergoing solid organ transplantation, the presence of an interleukin-1 (IL-1)
driven disease may require the addition of IL-1 inhibiting drugs to the standard …