Mesenchymal stem cell migration and tissue repair

X Fu, G Liu, A Halim, Y Ju, Q Luo, G Song - Cells, 2019 - mdpi.com
Mesenchymal stem cells (MSCs) are multilineage cells with the ability to self-renew and
differentiate into a variety of cell types, which play key roles in tissue healing and …

Mesenchymal stromal cell secretome: influencing therapeutic potential by cellular pre-conditioning

JR Ferreira, GQ Teixeira, SG Santos… - Frontiers in …, 2018 - frontiersin.org
Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …

Mesenchymal stem/stromal cell-based therapy: mechanism, systemic safety and biodistribution for precision clinical applications

WZ Zhuang, YH Lin, LJ Su, MS Wu, HY Jeng… - Journal of biomedical …, 2021 - Springer
Mesenchymal stem/stromal cells (MSCs) are a promising resource for cell-based therapy
because of their high immunomodulation ability, tropism towards inflamed and injured …

Mechanisms of mesenchymal stem/stromal cell function

JL Spees, RH Lee, CA Gregory - Stem cell research & therapy, 2016 - Springer
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …

Paracrine mechanisms of mesenchymal stem cells in tissue repair

M Gnecchi, P Danieli, G Malpasso… - Mesenchymal Stem Cells …, 2016 - Springer
Tissue regeneration from transplanted mesenchymal stromal cells (MSC) either through
transdifferentiation or cell fusion was originally proposed as the principal mechanism …

Ischemia-reperfusion injury reduces long term renal graft survival: mechanism and beyond

H Zhao, A Alam, AP Soo, AJT George, D Ma - EBioMedicine, 2018 - thelancet.com
Ischemia-reperfusion injury (IRI) during renal transplantation often initiates non-specific
inflammatory responses that can result in the loss of kidney graft viability. However, the long …

Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells

J Leibacher, R Henschler - Stem cell research & therapy, 2016 - Springer
Mesenchymal stem/stromal cells (MSCs) are increasingly used as an intravenously applied
cellular therapeutic. They were found to be potent in situations such as tissue repair or …

Shear-thinning hydrogels for biomedical applications

M Guvendiren, HD Lu, JA Burdick - Soft matter, 2012 - pubs.rsc.org
Injectable hydrogels are becoming increasingly important in the fields of tissue engineering
and drug delivery due to their tunable properties, controllable degradation, high water …

Trophic effects of mesenchymal stem cells in tissue regeneration

Y Fu, L Karbaat, L Wu, J Leijten, SK Both… - … Engineering Part B …, 2017 - liebertpub.com
Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …

Mesenchymal stem cells in health and disease

A Uccelli, L Moretta, V Pistoia - Nature reviews immunology, 2008 - nature.com
Mesenchymal stem cells (MSCs) are a heterogeneous subset of stromal stem cells that can
be isolated from many adult tissues. They can differentiate into cells of the mesodermal …