[HTML][HTML] The impact of systemic inflammation on Alzheimer's disease pathology

J Xie, L Van Hoecke, RE Vandenbroucke - Frontiers in immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a devastating age-related neurodegenerative disorder with an
alarming increasing prevalence. Except for the recently FDA-approved Aducanumab of …

The infectious etiology of Alzheimer's disease

M Sochocka, K Zwolinska… - Current …, 2017 - ingentaconnect.com
Background: Inflammation is a part of the first line of defense of the body against invasive
pathogens, and plays a crucial role in tissue regeneration and repair. A proper inflammatory …

Periodontitis and cognitive decline in Alzheimer's disease

M Ide, M Harris, A Stevens, R Sussams, V Hopkins… - PloS one, 2016 - journals.plos.org
Periodontitis is common in the elderly and may become more common in Alzheimer's
disease because of a reduced ability to take care of oral hygiene as the disease progresses …

Time to test antibacterial therapy in Alzheimer's disease

F Panza, M Lozupone, V Solfrizzi, M Watling… - Brain, 2019 - academic.oup.com
Alzheimer's disease is associated with cerebral accumulation of amyloid-β peptide and
hyperphosphorylated tau. In the past 28 years, huge efforts have been made in attempting to …

Alzheimer's disease and inflammaging

AM Kosyreva, AV Sentyabreva, IS Tsvetkov… - Brain sciences, 2022 - mdpi.com
Alzheimer's disease is one of the most common age-related neurodegenerative disorders.
The main theory of Alzheimer's disease progress is the amyloid-β cascade hypothesis …

[HTML][HTML] Periodontitis and Alzheimer's disease: a possible comorbidity between oral chronic inflammatory condition and neuroinflammation

FB Teixeira, MT Saito, FC Matheus… - Frontiers in aging …, 2017 - frontiersin.org
Periodontitis is an oral chronic infection/inflammatory condition, identified as a source of
mediators of inflammation into the blood circulation, which may contribute to exacerbate …

Oral microbiota and Alzheimer's disease: Do all roads lead to Rome?

A Sureda, M Daglia, SA Castilla, N Sanadgol… - Pharmacological …, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative pathology affecting milions of
people worldwide associated with deposition of senile plaques. While the genetic and …

Assessing the role of Porphyromonas gingivalis in periodontitis to determine a causative relationship with Alzheimer's disease

SK Singhrao, I Olsen - Journal of oral microbiology, 2019 - Taylor & Francis
Chronic periodontitis of 10 years' duration is reported to become a twofold risk factor for the
development of Alzheimer's disease (AD). Periodontitis is modifiable, and this fits with the …

[HTML][HTML] Infectious agents and Alzheimer's disease

T Piekut, M Hurła, N Banaszek, P Szejn… - Journal of Integrative …, 2022 - imrpress.com
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Individuals affected
by the disease gradually lose their capacity for abstract thinking, understanding …

The possibility of an infectious etiology of Alzheimer disease

GM Ashraf, VV Tarasov, A Makhmutovа… - Molecular …, 2019 - Springer
Over the past three decades, there has been constant postulation regarding the infectious
etiology of Alzheimer disease (AD), which in turn suggests the vital role of various infectious …