CRC is the third most commonly diagnosed malignancy and the fourth leading cause of
cancer-related death in the world. With advances in treatment, colorectal cancer is being …

Colorectal cancer is one of the most frequent solid tumors in the Western world. Treatment
options are dependent on the stage of the disease, the performance status of the patient …

This selection from the NCCN Guidelines for Rectal Cancer focuses on management of
malignant polyps and resectable nonmetastatic rectal cancer because important updates …

PURPOSE Prospective data on the efficacy of a watch-and-wait strategy to achieve organ
preservation in patients with locally advanced rectal cancer treated with total neoadjuvant …

The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

The incidence of rectal cancer in the European Union is $125 000 per year, ie $35% of the
total colorectal cancer incidence, reflecting 15–25 cases/100000 population per year and is …

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Rectal Cancer
address diagnosis, staging, surgical management, perioperative treatment, management of …

Importance Treatment of locally advanced rectal (LARC) cancer involves chemoradiation,
surgery, and chemotherapy. The concept of total neoadjuvant therapy (TNT), in which …

Japanese mortality due to colorectal cancer is on the rise, surpassing 49,000 in 2015. Many
new treatment methods have been developed during recent decades. The Japanese …

Background Patients with locally advanced rectal cancer who achieve a pathological
complete response to neoadjuvant chemoradiation have an improved prognosis. The need …