Episomal and chromosomal DNA replication and recombination in Entamoeba histolytica

S Bhattacharya - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Entamoeba histolytica is the causative agent of amoebiasis. DNA replication studies in E.
histolytica first started with the ribosomal RNA genes located on episomal circles. Unlike …

Evolution of Base Excision Repair in Entamoeba histolytica is shaped by gene loss, gene duplication, and lateral gene transfer

CH Trasviña-Arenas, SS David, L Delaye… - DNA repair, 2019 - Elsevier
During its life cycle, the protist parasite Entamoeba histolytica encounters reactive oxygen
and nitrogen species that alter its genome. Base excision repair (BER) is one of the most …

Proliferating cell nuclear antigen restores the enzymatic activity of a DNA ligase I deficient in DNA binding

CH Trasviña‐Arenas, CS Cardona‐Felix… - FEBS open …, 2017 - Wiley Online Library
Proliferating cell nuclear antigen (PCNA) coordinates multienzymatic reactions by
interacting with a variety of protein partners. Family I DNA ligases are multidomain proteins …

Structure and biochemical characterization of proliferating cellular nuclear antigen from a parasitic protozoon

CS Cardona-Felix, S Lara-Gonzalez… - … Section D: Biological …, 2011 - journals.iucr.org
Proliferating cellular nuclear antigen (PCNA) is a toroidal-shaped protein that is involved in
cell-cycle control, DNA replication and DNA repair. Parasitic protozoa are early-diverged …

The Sole DNA Ligase in Entamoeba histolytica Is a High-Fidelity DNA Ligase Involved in DNA Damage Repair

E Azuara-Liceaga, A Betanzos… - Frontiers in Cellular …, 2018 - frontiersin.org
The protozoan parasite Entamoeba histolytica is exposed to reactive oxygen and nitric oxide
species that have the potential to damage its genome. E. histolytica harbors enzymes …

[PDF][PDF] Recombinant Production of E. coli NAD+-dependent DNA ligase as a Target for Antibacterial Drug Discovery

Ö Kaplan, R İmamoğlu, İ Gökçe - Kahramanmaraş Sütçü İmam …, 2022 - dergipark.org.tr
The increase in the frequency of drug resistance in bacterial infections has led to the
research of new antibacterial agents targeting new mechanisms. Many of the functions of …

Archetypical and Specialized DNA Replication Proteins in Entamoeba histolytica

G Pastor-Palacios, V López-Ramírez… - Amebiasis: Biology and …, 2015 - Springer
Accurate DNA replication and repair are essential tasks for survival. In eukaryotes, DNA
polymerases replicate genomes that can be composed of billions of base pairs. These …