Environmental enrichment improves cognitive function, learning, memory and anxiety-related behaviours in rodent models of dementia: implications for future study

SNM Sahini, NAMN Hazalin, BN Srikumar… - … of Learning and …, 2024 - Elsevier
Environmental enrichment (EE) is a process of brain stimulation by modifying the
surroundings, for example, by changing the sensory, social, or physical conditions. Rodents …

[HTML][HTML] Barrier–environment interactions along the gut–brain axis and their influence on cognition and behaviour throughout the lifespan

SEJ Paton, JL Solano, F Coulombe-Rozon… - Journal of Psychiatry and …, 2023 - jpn.ca
Environment is known to substantially alter mental state and behaviour across the lifespan.
Biological barriers such as the blood–brain barrier (BBB) and gut barrier (GB) are major …

Sex differences in metabolic phenotype and hypothalamic inflammation in the 3xTg-AD mouse model of Alzheimer's disease

LS Robison, OJ Gannon, AE Salinero… - Biology of Sex …, 2023 - Springer
Background Alzheimer's disease (AD) is notably associated with cognitive decline resulting
from impaired function of hippocampal and cortical areas; however, several other domains …

Role of sex and high-fat diet in metabolic and hypothalamic disturbances in the 3xTg-AD mouse model of Alzheimer's disease

LS Robison, OJ Gannon, MA Thomas… - Journal of …, 2020 - Springer
Background Hypothalamic dysfunction occurs early in the clinical course of Alzheimer's
disease (AD), likely contributing to disturbances in feeding behavior and metabolic function …

Moderate exercise combined with enriched environment enhances learning and memory through BDNF/TrkB signaling pathway in rats

L Xu, L Zhu, L Zhu, D Chen, K Cai, Z Liu… - International journal of …, 2021 - mdpi.com
This study aimed to investigate the effects and potential mechanisms of exercise combined
with an enriched environment on learning and memory in rats. Forty healthy male Wistar rats …

On the application of developmental cognitive neuroscience in educational environments

G Leisman - Brain Sciences, 2022 - mdpi.com
The paper overviews components of neurologic processing efficiencies to develop
innovative methodologies and thinking to school-based applications and changes in …

Multisensory stimulation improves cognition and behavior in adult male rats born to LT4-treated thyroidectomized dams

A Batistuzzo, GG de Almeida, TS Brás… - …, 2022 - academic.oup.com
Gestational hypothyroidism can impair development, cognition, and mood. Here, we tested
whether multisensory stimulation (MS) improves the phenotype of rats born to surgically …

Environmental enrichment in murine models and its translation to human factors improving conditions in Alzheimer disease

MF Colavitta, L Grasso, FJ Barrantes - The Journal of Prevention of …, 2023 - Springer
With the aging of the world population, there has been a notable increase in the incidence of
Alzheimer disease (AD), the most prevalent neurodegenerative disease affecting the elderly …

The roles, mechanism, and mobilization strategy of endogenous neural stem cells in brain injury

H Liu, T Wei, Q Huang, W Liu, Y Yang, Y Jin… - Frontiers in Aging …, 2022 - frontiersin.org
Brain injury poses a heavy disease burden in the world, resulting in chronic deficits.
Therapies for brain injuries have been focused on pharmacologic, small molecule …

Noncognitive species-typical and home-cage behavioral alterations in conditional presenilin 1/presenilin 2 double knockout mice

Y Si, C Guo, F Xiao, B Mei, B Meng - Behavioural Brain Research, 2022 - Elsevier
Impairments in activities of daily living (ADL) are common clinical symptoms of human
Alzheimer's disease (AD). Describing the ADL in AD animal models might provide more …