Mitral valve disease is a frequent cause of heart failure and death. Emerging evidence
indicates that the mitral valve is not a passive structure, but—even in adult life—remains …

This revision of the “ACC/AHA/NASPE Guidelines for Implantation of Cardiac Pacemakers
and Antiarrhythmia Devices” updates the previous versions published in 1984, 1991, 1998 …

The online-only Data Supplement is available with this article at http://circ. ahajournals.
org/lookup/suppl/doi: 10.1161/CIR. 0b013e318276ce9b/-/DC1. The online-only …

Background Cardiac resynchronization therapy (CRT) is one of the most successful heart
failure therapies to emerge in the last 25 years and is applicable to∼ 25–30% of patients …

Background—Mechanical dyssynchrony is a potential means to predict response to cardiac
resynchronization therapy (CRT). We hypothesized that novel echocardiographic image …

Background Observational studies suggest that conventional right ventricular apical pacing
may have a deleterious effect on left ventricular function. In this study, we examined whether …

Echocardiography plays an evolving and important role in the care of heart failure patients
treated with biventricular pacing, or cardiac resynchronization therapy (CRT). Numerous …

dysfunction, decreasing the leaflet closing force, 22 as opposed to PM wall tethering.
Conceivably, however, the acute PM wall displacement in that study was insufficient to …

Importance Traditionally, physicians distinguished between mitral regurgitation (MR) as a
determinant of outcomes and MR as a biomarker of left-ventricular (LV) dysfunction by …

Background Conventional dual-chamber pacing maintains atrioventricular synchrony but
results in high percentages of ventricular pacing, which causes ventricular …