Obesity is a metabolic state generated by the expansion of adipose tissue. Adipose tissue
expansion depends on the interplay between hyperplasia and hypertrophy, and is mainly …

Background The relationships of the rs17782313 polymorphism near melanocortin 4
receptor gene (MC4R) and the rs8192678 polymorphism in peroxisome proliferator …

Obesity has become a common global problem. Some obese people can be metabolically
healthy. Gene-environment interaction can be important in this context. This study aimed to …

Context The melanocortin-4 receptor gene (MC4R) is associated with a higher risk of obesity
by the presence of the C allele in rs17782313, but the mechanisms are not clear. Objective …

Introduction Obesity is a multifactorial disease caused by an interaction between genetic,
environmental and behavioral factors. Polymorphisms of the two genes Circadian …

Introduction Appetitive traits are influenced by the interplay between genetic and
environmental factors. This study aimed to explore the relationship between gene …

The lining of our intestinal surface contains an array of hormone-producing cells that are
collectively our bodies' largest endocrine cell reservoir. These “enteroendocrine”(EE) cells …

Objective: Combining different pharmaceuticals may be beneficial when treating disorders
with complex neurobiology, including alcohol use disorder (AUD). The gut-brain peptides …

The global rise in obesity is attributed to genetic predisposition interaction with an
obesogenic environment. Melanocortin 4 receptor (MC4R) rs17782313 polymorphism has …

Aim: To analyze roles of single nucleotide variants (SNVs) on weight loss with US FDA-
approved medications. Materials & methods: We searched the literature up until November …