The historic term 'histiocytosis' meaning 'tissue cell'is used as a unifying concept for
diseases characterized by pathogenic myeloid cells that share histological features with …

Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors
that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ …

Langerhans-Cell Histiocytosis A spectrum of diseases formerly known as histiocytosis X and
now called Langerhans-cell histiocytosis is characterized by ERK pathway activation …

Abstract “Langerhans cell histiocytosis”(LCH) describes a spectrum of clinical presentations
ranging from a single bone lesion or trivial skin rash to an explosive disseminated disease …

Langerhans cell histiocytosis (LCH), the most common histiocytic disorder, is characterized
by the accumulation of CD 1A+/CD 207+ mononuclear phagocytes within granulomatous …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …

Langerhans cell histiocytosis is a rare clonal disease characterized by the proliferation of
CD1a-positive immature dendritic cells. The purpose of this article was to present an …

Lymphomas are the third most common malignancy among children and adolescents. 1, 2 In
children less than 15 years of age, non-Hodgkin Lymphoma (NHL) is more frequent; …

Background Langerhans cell histiocytosis (LCH) is a rare disease, frequently affecting
young children. Procedure We performed a retrospective study in patients younger than 16 …

Langerhans cell histiocytosis (LCH) is a disorder of myeloid neoplasia of dendritic cells that
affects 1 in 200,000 children< 15 years of age and even fewer adults. LCH presents with a …