Climate change is causing soil salinization, resulting in crop losses throughout the world.
The ability of plants to tolerate salt stress is determined by multiple biochemical and …

Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino
acid is:(i) A main precursor of extracellular collagens (the most abundant human proteins) …

Significance: Proline metabolism has complex roles in a variety of biological processes,
including cell signaling, stress protection, and energy production. Proline also contributes to …

The long slender bloodstream form Trypanosoma brucei maintains its essential
mitochondrial membrane potential (ΔΨm) through the proton-pumping activity of the FoF1 …

Sleeping sickness, also known as human African trypanosomiasis (HAT), is a neglected
disease that impacts 70 million people living in 1.55 million km2 in sub-Saharan Africa …

Cellular metabolic activity is a highly complex, dynamic, regulated process that is influenced
by numerous factors, including extracellular environmental signals, nutrient availability and …

The human pathogenic trypanosomatid species collectively called the “TriTryp parasites”–
Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp.–have complex life cycles …

Trypanosoma brucei, as well as Trypanosoma cruzi and more than 20 species of the genus
Leishmania, form a group of flagellated protists that threaten human health. These …

Amino acids are among the earliest identified inducers of yeast-to-hyphal transitions in
Candida albicans, an opportunistic fungal pathogen of humans. Here, we show that the …

In nearly all eukaryotes, cellular differentiation is governed by changes in transcription, and
stabilized by chromatin and DNA modification. Gene expression control in the pathogen …