Toll-like receptors and the control of immunity

KA Fitzgerald, JC Kagan - Cell, 2020 - cell.com
The study of innate immunity and its link to inflammation and host defense encompasses
diverse areas of biology, ranging from genetics and biophysics to signal transduction and …

The BET family in immunity and disease

N Wang, R Wu, D Tang, R Kang - Signal transduction and targeted …, 2021 - nature.com
Innate immunity serves as the rapid and first-line defense against invading pathogens, and
this process can be regulated at various levels, including epigenetic mechanisms. The …

Lactobacillus johnsonii alleviates colitis by TLR1/2-STAT3 mediated CD206+ macrophagesIL-10 activation

DJC Jia, QW Wang, YY Hu, JM He, QW Ge, YD Qi… - Gut …, 2022 - Taylor & Francis
Imbalance of gut microbiota homeostasis is related to the occurrence of ulcerative colitis
(UC), and probiotics are thought to modulate immune microenvironment and repair barrier …

Oral mucosal epithelial cells

S Groeger, J Meyle - Frontiers in immunology, 2019 - frontiersin.org
Cellular Phenotype and Apoptosis: The function of epithelial tissues is the protection of the
organism from chemical, microbial, and physical challenges which is indispensable for …

Can SARS-CoV-2 virus use multiple receptors to enter host cells?

LK Gadanec, KR McSweeney, T Qaradakhi… - International journal of …, 2021 - mdpi.com
The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …

Involvement of probiotics and postbiotics in the immune system modulation

N Yeşilyurt, B Yılmaz, D Ağagündüz, R Capasso - Biologics, 2021 - mdpi.com
Intestinal microbiota interacts with other systems, especially the immune system, which is
responsible for protecting the body by recognizing “stranger”(pathogen associated …

The history of Toll-like receptors—redefining innate immunity

LAJ O'neill, D Golenbock, AG Bowie - Nature Reviews Immunology, 2013 - nature.com
The discovery of Toll-like receptors (TLRs) was an important event for immunology research
and was recognized as such with the awarding of the 2011 Nobel Prize in Physiology or …

Role of microglia TLRs in neurodegeneration

BL Fiebich, CRA Batista, SW Saliba… - Frontiers in cellular …, 2018 - frontiersin.org
Toll-like receptors (TLRs) are a group of receptors widely distributed in the organism. In the
central nervous system, they are expressed in neurons, astrocytes and microglia. Although …

The emerging role of Toll-like receptor 4 in myocardial inflammation

Y Yang, J Lv, S Jiang, Z Ma, D Wang, W Hu… - Cell death & …, 2016 - nature.com
Toll-like receptors (TLRs) are a family of pattern recognition receptors involved in
cardiovascular diseases. Notably, numerous studies have demonstrated that TLR4 activates …

Toll-like receptors: activation, signalling and transcriptional modulation

D De Nardo - Cytokine, 2015 - Elsevier
Abstract Families of innate immune receptors serve as the bodies primary defence system
by recognising and rapidly responding to infection by microorganisms or to endogenous …