Drug nanoparticles embedded in a dispersant matrix as a secondary phase, ie, drug-laden
nanocomposites, offer a versatile delivery platform for enhancing the dissolution rate and …

Preparation of drug nanoparticles via wet media milling (nanomilling) is a very versatile drug
delivery platform and is suitable for oral, injectable, inhalable, and buccal applications. Wet …

Abstract Formulation of nanocrystals is a robust approach which can improve delivery of
poorly water soluble drugs, a challenge pharmaceutical industry has been facing since long …

In recent years, nanosuspension has been considered effective in the delivery of water-
soluble drugs. One of the main challenges to effective drug delivery is designing an …

Intravenous (IV) route is preferred for rapid onset of action, avoiding first pass metabolism
and achieving site specific delivery. Development of IV formulations for poorly water soluble …

Background Nanosuspensions, liquid dispersions with nanometer size distribution, are
becoming trendy in pharmaceutical practice to formulate poorly water-soluble drugs and to …

The quantitative determination of solubility and the initial dissolution rate enhancement of
crystalline nanoparticles were critically investigated using a separation-based approach …

Introduction: Nanosuspensions combine the advantages of nanotherapeutics (eg increased
dissolution rate and saturation solubility) with ease of commercialisation. Transformation of …

Quality by design (QbD) principles were implemented to understand the product and
process variables of sonoprecipitation technique, for preparation of eprosartan mesylate …

The aim of this work was to systematically study the effect of freeze-drying of bottom-up
processed cilostazol nanosuspension on the particle size after redispersion. Several …