This review is the sixth update of the original article published in 1999 on the application of
MALDI mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings …

O‐sulfation is an important chemical code widely existing in bioactive molecules, but the
scalable and facile synthesis of complex bioactive molecules carrying O‐sulfates remains …

The NMR experiment design strategy of NO Relaxation Delay (NORD), introduced mostly as
an idealized theoretical approach, is extended and put to practical use by considering …

Although hundreds of heparan sulfate (HS) binding proteins have been implicated in a
myriad of physiological and pathological processes, very little information is known about …

Resonance assignment is a pivotal step for any nuclear magnetic resonance (NMR)
analysis, such as structure elucidation or the investigation of protein–ligand interactions …

Researchers are paying increasing attention to the strongly negatively charged
heteropolysaccharides in cells, in the extracellular matrix or in the cell wall. Examples of …

The first total synthesis of neuritogenic ganglioside GAA‐7 was achieved using the glucosyl
ceramide (Glc‐Cer) cassette approach. The stereocenter triad within the ceramide moiety of …

This article delves into the synthesis and biological evaluation of sulfated and sulfonated
disaccharide analogs, exploring their interactions with toll-like receptor 4 (TLR4) and their …

Idraparinux, the fully O-sulfated, O-methylated, heparin-related pentasaccharide possessing
selective factor Xa inhibitory activity, was prepared by a new synthetic pathway. This route …

One critical part of the synthesis of heparinoid anticoagulants is the creation of the L-iduronic
acid building block featured with unique conformational plasticity which is crucial for the …