Fabry disease is a multi-organ disease, caused by mutations in the GLA gene and leading to
a progressive accumulation of glycosphingolipids due to enzymatic absence or malfunction …

Anderson–Fabry disease (AFD) is a genetic sphingolipidosis involving virtually the entire
body. Among its manifestation, the involvement of the central and peripheral nervous system …

Fabry disease (FD) is caused by α-galactosidase A (AGAL) enzyme deficiency, leading to
globotriaosylceramide accumulation (Gb3) in several cell types. Pain is one of the …

Patients with Fabry disease suffer from chronic debilitating pain and peripheral sensory
neuropathy with minimal treatment options, but the cellular drivers of this pain are unknown …

Fabry disease (FD) is a life-limiting disorder characterized by intracellular
globotriaosylceramide (Gb3) accumulations. The underlying α-galactosidase A (α-GAL A) …

Traditionally, peripheral sensory neurons are assumed as the exclusive transducers of
external stimuli. Current research moves epidermal keratinocytes into focus as sensors and …

Fabry disease (FD) is a lysosomal storage disorder of X-linked inheritance. Mutations in the
α-galactosidase A gene lead to cellular globotriaosylceramide (Gb3) depositions and …

Fabry disease (FD) is an X‐linked multiorgan disorder caused by variants in the alpha‐
galactosidase A gene (GLA). Depending on the variant, disease phenotypes range from …

Introduction Reprogramming of human-induced pluripotent stem cells (iPSCs) and their
differentiation into specific cell types, such as induced sensory-like neurons (iSNs), are …

Traditionally, peripheral sensory neurons are assumed as the exclusive transducers of
external stimuli. Current research moves epidermal keratinocytes into focus as sensors and …