Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …

Breathing is a vital rhythmic motor behavior with a surprisingly broad influence on the brain
and body. The apparent simplicity of breathing belies a complex neural control system, the …

Twenty‐five years ago, a new physiological preparation called the working heart–brainstem
preparation (WHBP) was introduced with the claim it would provide a new platform allowing …

Breathing needs to be tightly coordinated with upper airway behaviors, such as swallowing.
Discoordination leads to aspiration pneumonia, the leading cause of death in …

Collectively, the retrotrapezoid nucleus (RTN) and adjacent C1 neurons regulate breathing,
circulation and the state of vigilance, but previous methods to manipulate the activity of these …

The neurotransmitter glycine is an agonist at the strychnine‐sensitive glycine receptors. In
addition, it has recently been discovered to act at two new receptors, the excitatory glycine …

Active expiration is essential for increasing pulmonary ventilation during high chemical drive
(hypercapnia). The lateral parafacial (pFL) region, which contains expiratory neurones …

The lateral parafacial region (pFL; which encompasses the parafacial respiratory group,
pFRG) is a conditional oscillator that drives active expiration during periods of high …

Abstract Study Objectives Exposure to postnatal chronic intermittent hypoxia (pCIH), as
experienced in sleep-disordered breathing, is a risk factor for developing cardiorespiratory …

Tracing the evolution of the central rhythm generators associated with ventilation in
vertebrates is hindered by a lack of information surrounding key transitions. To begin with …