Induced models of osteoarthritis in animal models: a systematic review
UG Longo, R Papalia, S De Salvatore, R Picozzi… - Biology, 2023 - mdpi.com
Simple Summary This study aimed to determine the most appropriate animal model for the
study of osteoarthritis (OA). OA is a common joint disease and can be induced in animal …
study of osteoarthritis (OA). OA is a common joint disease and can be induced in animal …
Higher ratios of chondrocyte to mesenchymal stem cells elevate the therapeutic effects of extracellular vesicles harvested from chondrocyte/mesenchymal stem cell co …
M Hosseinzadeh, A Kamali… - Cell and Tissue …, 2023 - Springer
Extracellular vesicles (EVs) may have a key therapeutic role and offer an innovative
treatment for osteoarthritis (OA). Studies have shown that ratio of MSC/chondrocyte could …
treatment for osteoarthritis (OA). Studies have shown that ratio of MSC/chondrocyte could …
[HTML][HTML] Psoralen protects chondrocytes, exhibits anti-inflammatory effects on synoviocytes, and attenuates monosodium iodoacetate-induced osteoarthritis
C Wang, MK Al-Ani, Y Sha, Q Chi, N Dong… - … journal of biological …, 2019 - ncbi.nlm.nih.gov
Current study examined whether psoralen (PSO) exhibits anti-inflammatory responses,
protection and activation of chondrocytes, and relieve osteoarthritis (OA). Rats chondrocytes …
protection and activation of chondrocytes, and relieve osteoarthritis (OA). Rats chondrocytes …
Harpagide inhibits the TNF-α-induced inflammatory response in rat articular chondrocytes by the glycolytic pathways for alleviating osteoarthritis
C Xu, Y Tang, H Yang, S Jiang, W Peng… - International …, 2024 - Elsevier
Osteoarthritis (OA) causes severe and functional dysfunction due to abnormal inflammation.
The objective of this study was to evaluate the effect of Harpagide (HPG) on TNF-α-induced …
The objective of this study was to evaluate the effect of Harpagide (HPG) on TNF-α-induced …
Alpinetin Protects Chondrocytes and Exhibits Anti-Inflammatory Effects via the NF-κB/ERK Pathway for Alleviating Osteoarthritis
Y Gao, S Wang, L He, C Wang, L Yang - Inflammation, 2020 - Springer
Osteoarthritis (OA) is a chronic degenerative joint disease which is greatly affected by the
inflammatory response triggered by the NF-κB signaling pathway. Alpinetin (APT) is a …
inflammatory response triggered by the NF-κB signaling pathway. Alpinetin (APT) is a …
Magnolin exhibits anti-inflammatory effects on chondrocytes via the NF-κB pathway for attenuating anterior cruciate ligament transection-induced osteoarthritis
K Xu, Y Gao, L Yang, Y Liu, C Wang - Connective tissue research, 2021 - Taylor & Francis
Purpose: This study aimed to investigate whether magnolin (MGL) possesses the capability
of suppressing inflammatory responses that can in turn alleviate osteoarthritis (OA) …
of suppressing inflammatory responses that can in turn alleviate osteoarthritis (OA) …
[HTML][HTML] Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-ĸB pathway in …
L Yan, L Zhou, D Xie, W Du, F Chen, Q Yuan… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Platelet lysate (PL) contains a cocktail of growth factors that actively participates in cartilage
repair. This study was designed to determine the effect and mechanism of PL on …
repair. This study was designed to determine the effect and mechanism of PL on …
Assessment of the Efficacy of Bone Marrow‐Derived Mesenchymal Stem Cells against a Monoiodoacetate‐Induced Osteoarthritis Model in Wistar Rats
HM Hamdalla, RR Ahmed, SR Galaly… - Stem Cells …, 2022 - Wiley Online Library
Osteoarthritis (OA) of the knee is a debilitating condition that can severely limit an
individual's mobility and quality of life. This study was designed to evaluate the efficacy of …
individual's mobility and quality of life. This study was designed to evaluate the efficacy of …
[HTML][HTML] The Oral Administration of Lactobacillus delbrueckii subsp. lactis 557 (LDL557) Ameliorates the Progression of Monosodium Iodoacetate-Induced …
LW Huang, TC Huang, YC Hu, BS Hsieh… - Current Issues in …, 2024 - mdpi.com
Low-grade body inflammation is a major cause of osteoarthritis (OA), a common joint
disease. Gut dysbiosis may lead to systemic inflammation which can be prevented by …
disease. Gut dysbiosis may lead to systemic inflammation which can be prevented by …
Interleukin‐17 Can Induce Osteoarthritis in Rabbit Knee Joints Similar to Hulth's Method
Z Wang, C Zheng, Y Zhong, J He, X Cao… - BioMed Research …, 2017 - Wiley Online Library
Interleukin‐17 (IL‐17) is closely related to osteoarthritis (OA), but animal studies that employ
IL‐17 to induce OA are currently lacking. Therefore, this study evaluated the effect of IL‐17 in …
IL‐17 to induce OA are currently lacking. Therefore, this study evaluated the effect of IL‐17 in …