Engineered living materials for sustainability

B An, Y Wang, Y Huang, X Wang, Y Liu, D Xun… - Chemical …, 2022 - ACS Publications
Recent advances in synthetic biology and materials science have given rise to a new form of
materials, namely engineered living materials (ELMs), which are composed of living matter …

A self-powered ingestible wireless biosensing system for real-time in situ monitoring of gastrointestinal tract metabolites

E De la Paz, NH Maganti, A Trifonov, I Jeerapan… - Nature …, 2022 - nature.com
Abstract Information related to the diverse and dynamic metabolite composition of the small
intestine is crucial for the diagnosis and treatment of various diseases. However, our current …

[HTML][HTML] Perspective: challenges and future directions in clinical research with nuts and berries

ML Zuelch, MD Radtke, RR Holt, A Basu… - Advances in …, 2023 - Elsevier
Consumption of nuts and berries are considered part of a healthy eating pattern. Nuts and
berries contain a complex nutrient profile, consisting of essential vitamins and minerals …

Intestinal engineered probiotics as living therapeutics: chassis selection, colonization enhancement, gene circuit design, and biocontainment

Y Huang, X Lin, S Yu, R Chen, W Chen - ACS synthetic biology, 2022 - ACS Publications
Intestinal probiotics are often used for the in situ treatment of diseases, such as metabolic
disorders, tumors, and chronic inflammatory infections. Recently, there has been an …

Characterization of eight bacterial biosensors for microbial diagnostic and therapeutic applications

TH Vaaben, R Vazquez-Uribe… - ACS Synthetic …, 2022 - ACS Publications
The engineering of microbial cells to produce and secrete therapeutics directly in the human
body, known as advanced microbial therapeutics, is an exciting alternative to current drug …

Current status and future directions of ingestible electronic devices in gastroenterology

PA Thwaites, CK Yao, EP Halmos… - Alimentary …, 2024 - Wiley Online Library
Background Advances in microelectronics have greatly expanded the capabilities and
clinical potential of ingestible electronic devices. Aim To provide an overview of the structure …

Achieving spatially precise diagnosis and therapy in the mammalian gut using synthetic microbial gene circuits

CM Robinson, NE Short, DT Riglar - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The mammalian gut and its microbiome form a temporally dynamic and spatially
heterogeneous environment. The inaccessibility of the gut and the spatially restricted nature …

A threshold-based bioluminescence detector with a CMOS-integrated photodiode array in 65 nm for a multi-diagnostic ingestible capsule

Q Liu, M Jimenez, ME Inda, A Riaz… - IEEE Journal of Solid …, 2022 - ieeexplore.ieee.org
This article presents a highly miniaturized ingestible electronic capsule for biochemical
detection via onboard genetically engineered biosensor bacteria. The core integrated circuit …

Prebiotics-controlled disposable engineered bacteria for intestinal diseases

TT Fang, ZP Zou, Y Zhou, BC Ye - ACS Synthetic Biology, 2022 - ACS Publications
As a new method of diagnosis and treatment for intestinal diseases, intelligent engineered
bacteria based on synthetic biology have been developed vigorously in recent years …

微生物合成生物学在疾病诊疗上的应用进展

高纤云, 牛灵雪, 见妮, 管宁子 - 合成生物学, 2023 - synbioj.cip.com.cn
在人体的身体内部居住着数以万亿计的细菌和其他微生物, 寄生在我们的皮肤,
胃肠道和口腔等部位, 微生物群失调已成为炎症性肠病, 过敏, 肥胖, 心血管以及神经退行性疾病 …