When worlds collide: Th17 and Treg cells in cancer and autoimmunity

HM Knochelmann, CJ Dwyer, SR Bailey… - Cellular & molecular …, 2018 - nature.com
The balance between Th17 cells and regulatory T cells (Tregs) has emerged as a prominent
factor in regulating autoimmunity and cancer. Th17 cells are vital for host defense against …

[HTML][HTML] A cellular and molecular view of T helper 17 cell plasticity in autoimmunity

R Stadhouders, E Lubberts, RW Hendriks - Journal of autoimmunity, 2018 - Elsevier
Since the original identification of the T helper 17 (Th17) subset in 2005, it has become
evident that these cells do not only contribute to host defence against pathogens, such as …

IL-9 aggravates SARS-CoV-2 infection and exacerbates associated airway inflammation

S Sadhu, R Dalal, J Dandotiya, A Binayke… - Nature …, 2023 - nature.com
SARS-CoV-2 infection is known for causing broncho-alveolar inflammation. Interleukin 9 (IL-
9) induces airway inflammation and bronchial hyper responsiveness in respiratory viral …

High-salt diet mediates interplay between NK cells and gut microbiota to induce potent tumor immunity

ZA Rizvi, R Dalal, S Sadhu, Y Kumar, S Kumar… - Science …, 2021 - science.org
High-salt diet (HSD) modulates effector and regulatory T cell functions and promotes tissue
inflammation in autoimmune diseases. However, effects of HSD and its association with gut …

Nutrients mediate intestinal bacteria–mucosal immune crosstalk

N Ma, P Guo, J Zhang, T He, SW Kim… - Frontiers in …, 2018 - frontiersin.org
The intestine is the shared site of nutrient digestion, microbiota colonization and immune cell
location and this geographic proximity contributes to a large extent to their interaction. The …

Golden Syrian hamster as a model to study cardiovascular complications associated with SARS-CoV-2 infection

ZA Rizvi, R Dalal, S Sadhu, A Binayke, J Dandotiya… - Elife, 2022 - elifesciences.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the Golden
Syrian hamster causes lung pathology that resembles human coronavirus disease (COVID …

IL-9-producing T cells: potential players in allergy and cancer

P Angkasekwinai, C Dong - Nature Reviews Immunology, 2021 - nature.com
Abstract IL-9-producing CD4+ T cells have been considered to represent a distinct T helper
cell (TH cell) subset owing to their unique developmental programme in vitro, their …

Nanostructured titanium regulates osseointegration via influencing macrophage polarization in the osteogenic environment

J Wang, F Meng, W Song, J Jin, Q Ma… - International journal …, 2018 - Taylor & Francis
Introduction Fabricating nanostructured surface topography represents the mainstream
approach to induce osteogenesis for the next-generation bone implant. In the past, the bone …

Pharmacological potential of Withania somnifera (L.) Dunal and Tinospora cordifolia (Willd.) Miers on the experimental models of COVID-19, T cell differentiation …

ZA Rizvi, P Babele, U Madan, S Sadhu… - Frontiers in …, 2023 - frontiersin.org
Cytokine release syndrome (CRS) due to severe acute respiratory coronavirus-2 (SARS-
CoV-2) infection leads to life-threatening pneumonia which has been associated with …

HLA-Class II Artificial Antigen Presenting Cells in CD4+ T Cell-Based Immunotherapy

A Couture, A Garnier, F Docagne, O Boyer… - Frontiers in …, 2019 - frontiersin.org
CD4+ T cells differentiate into various T helper subsets characterized by distinct cytokine
secreting profiles that confer them effector functions adapted to a variety of infectious or …