Targeting immune checkpoints on tumor-associated macrophages in tumor immunotherapy
S Xu, C Wang, L Yang, J Wu, M Li, P Xiao… - Frontiers in …, 2023 - frontiersin.org
Unprecedented breakthroughs have been made in cancer immunotherapy in recent years.
Particularly immune checkpoint inhibitors have fostered hope for patients with cancer …
Particularly immune checkpoint inhibitors have fostered hope for patients with cancer …
A review of biomarkers and their clinical impact in resected early-stage non-small-cell lung cancer
W Cao, Q Tang, J Zeng, X Jin, L Zu, S Xu - Cancers, 2023 - mdpi.com
Simple Summary Non-small-cell lung cancer (NSCLC) accounts for approximately 85% of
all lung cancers, and the postoperative survival of early-stage NSCLC patients remains …
all lung cancers, and the postoperative survival of early-stage NSCLC patients remains …
Cross-talk between cuproptosis and ferroptosis regulators defines the tumor microenvironment for the prediction of prognosis and therapies in lung adenocarcinoma
Y Shen, D Li, Q Liang, M Yang, Y Pan, H Li - Frontiers in immunology, 2023 - frontiersin.org
Cuproptosis, a newly identified form of programmed cell death, plays vital roles in
tumorigenesis. However, the interconnectivity of cuproptosis and ferroptosis is poorly …
tumorigenesis. However, the interconnectivity of cuproptosis and ferroptosis is poorly …
Down-regulation of DNA key protein-FEN1 inhibits OSCC growth by affecting immunosuppressive phenotypes via IFN-γ/JAK/STAT-1
S Wang, X Wang, J Sun, J Yang, D Wu, F Wu… - International Journal of …, 2023 - nature.com
Oral squamous cell carcinoma (OSCC) escape from the immune system is mediated through
several immunosuppressive phenotypes that are critical to the initiation and progression of …
several immunosuppressive phenotypes that are critical to the initiation and progression of …
[HTML][HTML] Organ-specific heterogeneity in tumor-infiltrating immune cells and cancer antigen expression in primary and autologous metastatic lung adenocarcinoma
D Restle, J Dux, X Li, AJ Byun, JK Choe… - … for Immunotherapy of …, 2023 - ncbi.nlm.nih.gov
Background Tumor immune microenvironment (TIME) and cancer antigen expression, key
factors for the development of immunotherapies, are usually based on the data from primary …
factors for the development of immunotherapies, are usually based on the data from primary …
Clinical implications and molecular features of tertiary lymphoid structures in stage I lung adenocarcinoma
X Xu, Y Gao, S Duan, Q Ding, X Wang, X Dai… - Cancer …, 2023 - Wiley Online Library
Aims We investigated the clinical implications and molecular features of TLS in stage I lung
adenocarcinoma (LUAD). Methods We retrospectively reviewed the clinicopathological …
adenocarcinoma (LUAD). Methods We retrospectively reviewed the clinicopathological …
Tumor‐related exosomal circ_0001715 promotes lung adenocarcinoma cell proliferation and metastasis via enhancing M2 macrophage polarization by regulating …
M Chen, C Cao, J Ma - Thoracic Cancer, 2024 - Wiley Online Library
Abstract Background Circular RNAs (circRNAs) have been shown to mediate tumor‐
associated macrophages (TAMs) to regulate the development of many cancers, including …
associated macrophages (TAMs) to regulate the development of many cancers, including …
Combinational CAR T-cell therapy for solid tumors: Requisites, rationales, and trials
Chimeric antigen receptor (CAR) T-cell therapy has achieved potent antitumor efficacy in
hematological malignancies; however, because of limitations in CAR T-cell recruitment …
hematological malignancies; however, because of limitations in CAR T-cell recruitment …
Integrative tumour mutation burden with CD39 and PD-L1 for the prediction of response to PD-L1 blockade and adjuvant chemotherapy in muscle-invasive bladder …
C Liu, Z Liu, K Jin, H Zeng, F Shao, Y Chang… - British Journal of …, 2022 - nature.com
Background CD39, a rate-limiting enzyme to convert extracellular ATP (eATP) to adenosine,
has been reported to be a key modulator of immune response, but its correlation with …
has been reported to be a key modulator of immune response, but its correlation with …
Immune infiltration landscape on prognosis and therapeutic response and relevant epigenetic and transcriptomic mechanisms in lung adenocarcinoma
L Zhang, B Jiang, Z Lan, C Yang, Y Yao, J Lin… - Frontiers in …, 2022 - frontiersin.org
Objective Lung adenocarcinoma (LUAD) is the most prevalent lung cancer subtype, but its
immune infiltration features are not comprehensively understood. To address the issue, the …
immune infiltration features are not comprehensively understood. To address the issue, the …