The role of a gut microbial-derived metabolite, trimethylamine N-oxide (TMAO), in neurological disorders
SS Praveenraj, S Sonali, N Anand, HA Tousif… - Molecular …, 2022 - Springer
Trimethylamine lyases are expressed in a wide range of intestinal microbiota which
metabolize dietary nutrients like choline, betaine, and L-carnitine to form trimethylamine …
metabolize dietary nutrients like choline, betaine, and L-carnitine to form trimethylamine …
[HTML][HTML] Mitochondrial effects of common cardiovascular medications: the good, the bad and the mixed
AM Bețiu, L Noveanu, IM Hâncu, A Lascu… - International Journal of …, 2022 - mdpi.com
Mitochondria are central organelles in the homeostasis of the cardiovascular system via the
integration of several physiological processes, such as ATP generation via oxidative …
integration of several physiological processes, such as ATP generation via oxidative …
[HTML][HTML] Protective effect of renin-angiotensin system inhibitors on Parkinson's disease: a nationwide cohort study
Background: Renin-angiotensin system (RAS) inhibitors have been suggested as protective
agents in Parkinson's disease (PD). However, epidemiological evidence on the association …
agents in Parkinson's disease (PD). However, epidemiological evidence on the association …
Redox modulation of mitochondrial proteins in the neurotoxicant models of Parkinson's disease
A Sarkar, MSU Rasheed, MP Singh - Antioxidants & Redox …, 2023 - liebertpub.com
Significance: Mitochondrial proteins regulate the oxidative phosphorylation, cellular
metabolism, and free radical generation. Redox modulation alters the mitochondrial proteins …
metabolism, and free radical generation. Redox modulation alters the mitochondrial proteins …
Metastasis‐associated 1 localizes to the sarcomeric Z‐disc and is implicated in skeletal muscle pathology
H Xue, L Han, H Sun, Z Piao, W Cao, H Qian… - …, 2024 - Wiley Online Library
Abstract Metastasis‐associated 1 (MTA1), a subunit of the nucleosome remodeling and
histone deacetylation (NuRD) corepressor complex, was reported to be expressed in the …
histone deacetylation (NuRD) corepressor complex, was reported to be expressed in the …
[HTML][HTML] Telmisartan Protects Mitochondrial Function, Gait, and Neuronal Apoptosis by Activating the Akt/GSK3β/PGC1α Pathway in an MPTP-Induced Mouse Model of …
Background: Mitochondrial dysfunction is one of the major hallmarks of Parkinson's disease
(PD). Recently, angiotensin II type 1 and type 2 receptors (AT1R, AT2R) were reported to be …
(PD). Recently, angiotensin II type 1 and type 2 receptors (AT1R, AT2R) were reported to be …
Novel therapeutic targets to halt the progression of Parkinson's disease: an in-depth review on molecular signalling cascades
SK Meheronnisha, D Thekkekkara, A Babu, YM Tausif… - 3 Biotech, 2023 - Springer
Recent research has focused mostly on understanding and combating the
neurodegenerative mechanisms and symptoms of Parkinson's disease (PD). Moreover …
neurodegenerative mechanisms and symptoms of Parkinson's disease (PD). Moreover …
Valsartan Protects in High Fat Diet During Ischemic Reperfusion Injury
Aim: The study investigates the effect of Valsartan, an Angiotensin II type 1 receptor blocker
(ARB), on the blunted neuroprotective response of ischemic post-conditioning (iPoCo) in …
(ARB), on the blunted neuroprotective response of ischemic post-conditioning (iPoCo) in …