Advances in fatty acids nutrition in dairy cows: from gut to cells and effects on performance

M Bionaz, E Vargas-Bello-Pérez, S Busato - Journal of Animal Science …, 2020 - Springer
High producing dairy cows generally receive in the diet up to 5–6% of fat. This is a relatively
low amount of fat in the diet compared to diets in monogastrics; however, dietary fat is …

Biosynthesis of milk fat, protein, and lactose: roles of transcriptional and posttranscriptional regulation

JS Osorio, J Lohakare, M Bionaz - Physiological genomics, 2016 - journals.physiology.org
The demand for high-quality milk is increasing worldwide. The efficiency of milk synthesis
can be improved by taking advantage of the accumulated knowledge of the transcriptional …

KEGG-PATH: Kyoto encyclopedia of genes and genomes-based pathway analysis using a path analysis model

J Du, Z Yuan, Z Ma, J Song, X Xie, Y Chen - Molecular BioSystems, 2014 - pubs.rsc.org
The dynamic impact approach (DIA) represents an alternative to overrepresentation analysis
(ORA) for functional analysis of time-course experiments or those involving multiple …

Functional role of PPARs in ruminants: Potential targets for fine‐tuning metabolism during growth and lactation

M Bionaz, S Chen, MJ Khan, JJ Loor - PPAR research, 2013 - Wiley Online Library
Characterization and biological roles of the peroxisome proliferator‐activated receptor
(PPAR) isotypes are well known in monogastrics, but not in ruminants. However, a wealth of …

PPARγ Regulates Genes Involved in Triacylglycerol Synthesis and Secretion in Mammary Gland Epithelial Cells of Dairy Goats

H Shi, J Luo, J Zhu, J Li, Y Sun, X Lin, L Zhang… - PPAR …, 2013 - Wiley Online Library
To explore the function of PPARγ in the goat mammary gland, we cloned the whole cDNA of
the PPARγ gene. Homology alignments revealed that the goat PPARγ gene is conserved …

Transcriptional profiling of mammary gland in Holstein cows with extremely different milk protein and fat percentage using RNA sequencing

X Cui, Y Hou, S Yang, Y Xie, S Zhang, Y Zhang… - BMC genomics, 2014 - Springer
Abstract Background Recently, RNA sequencing (RNA-seq) has rapidly emerged as a major
transcriptome profiling system. Elucidation of the bovine mammary gland transcriptome by …

[HTML][HTML] MicroRNA expression patterns in the bovine mammary gland are affected by stage of lactation

M Wang, S Moisá, MJ Khan, J Wang, D Bu… - Journal of dairy science, 2012 - Elsevier
The objective of this work was to determine the expression pattern of microRNA (miR)
associated with cellular proliferation, lipid metabolism, and innate immunity in dairy cow …

A genome-wide association study for clinical mastitis in first parity US Holstein cows using single-step approach and genomic matrix re-weighting procedure

F Tiezzi, KL Parker-Gaddis, JB Cole, JS Clay… - PLoS …, 2015 - journals.plos.org
Clinical mastitis (CM) is one of the health disorders with large impacts on dairy farming
profitability and animal welfare. The objective of this study was to perform a genome-wide …

Systems physiology in dairy cattle: nutritional genomics and beyond

JJ Loor, M Bionaz, JK Drackley - Annu. Rev. Anim. Biosci., 2013 - annualreviews.org
Microarray development changed the way biologists approach the holistic study of cells and
tissues. In dairy cattle biosciences, the application of omics technology, from spotted …

[HTML][HTML] Genome-wide association analysis and pathways enrichment for lactation persistency in Canadian Holstein cattle

DN Do, N Bissonnette, P Lacasse, F Miglior… - Journal of Dairy …, 2017 - Elsevier
Lactation persistency (LP), defined as the rate of declining milk yield after milk peak, is an
economically important trait for dairy cattle. Improving LP is considered a good alternative …