RNA viruses carry out selective packaging of their genomes in a variety of ways, many
involving a genomic packaging signal. The first coronavirus packaging signal was …

The ongoing COVID-19 pandemic has caused an unprecedented global health crisis.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of …

Alternative polyadenylation (APA) is a widespread and conserved regulatory mechanism
that generates diverse 3′ ends on mRNA. APA patterns are often tissue specific and play …

Despite increased overall survival rates, curative options for metastatic breast cancer remain
limited. We have previously shown that metadherin (MTDH) is frequently overexpressed in …

Innate immune responses induce hundreds of interferon-stimulated genes (ISGs). Viperin, a
member of the radical S-adenosyl methionine (SAM) superfamily of enzymes, is the product …

Spatial segregation of mRNAs in the cytoplasm of cells is a well‐known biological
phenomenon that is widely observed in diverse species spanning different kingdoms of life …

Proteins are positioned and act at defined subcellular locations. This is particularly important
in eukaryotic cells that deliver proteins to membrane-bound organelles such as the …

Altered expression of many genes and proteins is essential for cancer development and
progression. Recently, the affected expression of metadherin (MTDH), also known as AEG-1 …

In light of the numerous studies identifying post-transcriptional regulators on the surface of
the endoplasmic reticulum (ER), we asked whether there are factors that regulate …

Stress granules (SGs) are membraneless organelles composed of mRNAs and RNA binding
proteins which undergo assembly in response to stress-induced inactivation of translation …