Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

P Düsing, A Zietzer, PR Goody, MR Hosen… - Journal of molecular …, 2021 - Springer
Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

Biological effects of sunlight, ultraviolet radiation, visible light, infrared radiation and vitamin D for health

MF Holick - Anticancer research, 2016 - ar.iiarjournals.org
Humans evolved in sunlight and had depended on sunlight for its life giving properties that
was appreciated by our early ancestors. However, for more than 40 years the lay press and …

Role of vitamin D in atherosclerosis

E Kassi, C Adamopoulos, EK Basdra… - Circulation, 2013 - Am Heart Assoc
It is well known that endothelium is the key vessel wall component in the initiation of the
atherogenic process. Its possible role in the later stages has been strongly suggested. 17 …

Vitamin D and diabetes

T Takiishi, C Gysemans, R Bouillon… - Rheumatic Disease …, 2012 - rheumatic.theclinics.com
Diabetes mellitus is one of the most common endocrine diseases, characterized by an
increase in plasma glucose. Different forms of diabetes with very distinct pathogenesis exist …

Fibroblast growth factor-23 and death, heart failure, and cardiovascular events in community-living individuals: CHS (Cardiovascular Health Study)

JH Ix, R Katz, BR Kestenbaum, IH de Boer… - Journal of the American …, 2012 - jacc.org
Objectives: This study sought to determine the association of fibroblast growth factor (FGF)-
23 with death, heart failure (HF), and cardiovascular disease (CVD) in the general …

Extraskeletal actions of vitamin D

DD Bikle - Annals of the New York academy of sciences, 2016 - Wiley Online Library
The vitamin D receptor (VDR) is found in nearly all, if not all, cells in the body. The enzyme
that produces the active metabolite of vitamin D and ligand for VDR, namely CYP27B1 …

Latest knowledge on the role of vitamin D in hypertension

NS Jensen, M Wehland, PM Wise, D Grimm - International Journal of …, 2023 - mdpi.com
Hypertension is the third leading cause of the global disease burden, and while populations
live longer, adopt more sedentary lifestyles, and become less economically concerned, the …

Vitamin D status and mortality risk in CKD: a meta-analysis of prospective studies

S Pilz, S Iodice, A Zittermann, WB Grant… - American Journal of …, 2011 - Elsevier
BACKGROUND: Vitamin D deficiency, assessed as low 25-hydroxyvitamin D (25 [OH] D)
level, is highly prevalent in patients with chronic kidney disease (CKD) and is associated …

Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in haemodialysis patients

C Drechsler, S Pilz, B Obermayer-Pietsch… - European heart …, 2010 - academic.oup.com
Aims Dialysis patients experience an excess mortality, predominantly of sudden cardiac
death (SCD). Accumulating evidence suggests a role of vitamin D for myocardial and overall …

The role of vitamin D and its molecular bases in insulin resistance, diabetes, metabolic syndrome, and cardiovascular disease: state of the art

C Argano, L Mirarchi, S Amodeo, V Orlando… - International Journal of …, 2023 - mdpi.com
In the last decade, an increasing awareness was directed to the role of Vitamin D in non-
skeletal and preventive roles for chronic diseases. Vitamin D is an essential hormone in …