Microbial production of natural and non-natural flavonoids: pathway engineering, directed evolution and systems/synthetic biology

RP Pandey, P Parajuli, MAG Koffas, JK Sohng - Biotechnology advances, 2016 - Elsevier
In this review, we address recent advances made in pathway engineering, directed
evolution, and systems/synthetic biology approaches employed in the production and …

Microbial biotransformation of bioactive flavonoids

H Cao, X Chen, AR Jassbi, J Xiao - Biotechnology Advances, 2015 - Elsevier
The bioactive flavonoids are considered as the most important phytochemicals in food,
which exert a wide range of biological benefits for human being. Microbial biotransformation …

Flavonoids, terpenoids, and polyketide antibiotics: Role of glycosylation and biocatalytic tactics in engineering glycosylation

UM Vasudevan, EY Lee - Biotechnology advances, 2020 - Elsevier
Flavonoids, terpenoids, and polyketides are structurally diverse secondary metabolites used
widely as pharmaceuticals and nutraceuticals. Most of these molecules exist in nature as …

Characterization and evaluation of antibacterial and wound healing activity of naringenin-loaded polyethylene glycol/polycaprolactone electrospun nanofibers

MH Farzaei, P Derayat, Z Pourmanouchehri… - Journal of Drug Delivery …, 2023 - Elsevier
Antibiotic resistance is one of the main reasons for the prolonged wound-healing process in
the world. Therefore, natural compounds that possess excellent antioxidant, anti …

Suppression of colorectal carcinogenesis by naringin

B Ansari, M Aschner, Y Hussain, T Efferth, H Khan - Phytomedicine, 2022 - Elsevier
Background Colorectal cancer is the third most malignant cancer worldwide. Despite novel
treatment options, the incidence and mortality rates of colon cancer continue to increase in …

How do biocatalysis and biotransformation affect Citrus dietary flavonoids chemistry and bioactivity? A review

ZTA Shakour, NM Fayek, MA Farag - Critical reviews in …, 2020 - Taylor & Francis
Flavonoids, especially flavanones, flavones and polymethoxyflavones (PMFs) are distinctive
bioactive compounds of Citrus fruits. Citrus peel and juice by-products potentially represent …

Biotechnological production of pharmaceuticals and biopharmaceuticals in plant cell and organ cultures

D Hidalgo, R Sanchez, L Lalaleo… - Current medicinal …, 2018 - ingentaconnect.com
Background: Plant biofactories are biotechnological platforms based on plant cell and organ
cultures used for the production of pharmaceuticals and biopharmaceuticals, although to …

Towards the synthesis of glycosylated dihydrochalcone natural products using glycosyltransferase-catalysed cascade reactions

A Gutmann, L Bungaruang, H Weber, M Leypold… - Green chemistry, 2014 - pubs.rsc.org
Regioselective O-β-D-glucosylation of flavonoid core structures is used in plants to create
diverse natural products. Their prospective application as functional food and …

Combinatorial biosynthesis in plants: a (p) review on its potential and future exploitation

J Pollier, T Moses, A Goossens - Natural product reports, 2011 - pubs.rsc.org
Covering: 2003 to 2011 Combinatorial biochemistry, also called combinatorial biosynthesis,
comprises a series of methods that establish novel enzyme–substrate combinations in vivo …

Anti-inflammatory and antioxidant jasmonates and flavonoids from lychee seeds

X Dong, Y Huang, Y Wang, X He - Journal of Functional Foods, 2019 - Elsevier
Abstract Lychee (Litchi chinensis Sonn.) is a famous tropical fruit. While enjoying its
delicacy, it also produces a lot of lychee seeds as waste. In this study, bioactive …