Exploring miRNA based approaches in cancer diagnostics and therapeutics

S Mishra, T Yadav, V Rani - Critical reviews in oncology/hematology, 2016 - Elsevier
MicroRNAs (miRNAs), a highly conserved class of tissue specific, small non-protein coding
RNAs maintain cell homeostasis by negative gene regulation. Proper controlling of miRNA …

microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

[HTML][HTML] Plasma exosome microRNAs are indicative of breast cancer

BN Hannafon, YD Trigoso, CL Calloway, YD Zhao… - Breast cancer …, 2016 - Springer
Background microRNAs are promising candidate breast cancer biomarkers due to their
cancer-specific expression profiles. However, efforts to develop circulating breast cancer …

[HTML][HTML] Potential prognostic biomarkers of NIMA (Never in Mitosis, Gene A)-Related Kinase (NEK) family members in breast cancer

G Anuraga, WJ Wang, NN Phan, NT An Ton… - Journal of personalized …, 2021 - mdpi.com
Breast cancer remains the most common malignant cancer in women, with a staggering
incidence of two million cases annually worldwide; therefore, it is crucial to explore novel …

Machine learning integrated ensemble of feature selection methods followed by survival analysis for predicting breast cancer subtype specific miRNA biomarkers

JP Sarkar, I Saha, A Sarkar, U Maulik - Computers in Biology and Medicine, 2021 - Elsevier
Breast cancer is the second leading cancer type among females. In this regard, it is found
that microRNAs play an important role by regulating the gene expressions at the post …

[HTML][HTML] Recent trends in microRNA research into breast cancer with particular focus on the associations between microRNAs and intrinsic subtypes

S Kurozumi, Y Yamaguchi, M Kurosumi… - Journal of human …, 2017 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs that regulate the function of target genes
at the post-transcriptional phase. miRNAs are considered to have roles in the development …

[HTML][HTML] Plasma miR-21, miR-155, miR-10b, and Let-7a as the potential biomarkers for the monitoring of breast cancer patients

S Khalighfard, AM Alizadeh, S Irani, R Omranipour - Scientific reports, 2018 - nature.com
There is a pressing need for further studies to categorize and validate circulating microRNAs
(miRs) in breast cancer patients that can be one of the novel strategies for cancer screening …

[HTML][HTML] Circulating microRNAs as potential biomarkers in pancreatic cancer—advances and challenges

AA Seyhan - International journal of molecular sciences, 2023 - mdpi.com
There is an urgent unmet need for robust and reliable biomarkers for early diagnosis,
prognosis, and prediction of response to specific treatments of many aggressive and deadly …

[HTML][HTML] A novel panel of serum miR-21/miR-155/miR-365 as a potential diagnostic biomarker for breast cancer

JG Han, YD Jiang, CH Zhang… - Annals of surgical …, 2017 - synapse.koreamed.org
Purpose Insufficient sensitivity and specificity prevent the use of most existing biomarkers for
early detection of breast cancer. Recently, it was reported that serum microRNAs (miRNAs) …

[HTML][HTML] Exosome‑encapsulated microRNA‑223‑3p as a minimally invasive biomarker for the early detection of invasive breast cancer

M Yoshikawa, H Iinuma, Y Umemoto… - Oncology …, 2018 - spandidos-publications.com
Patients diagnosed preoperatively with ductal carcinoma in situ (DCIS) breast cancer have
the potential to develop invasive ductal carcinoma (IDC). The present study investigated the …