The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …

Boron-containing compounds (BCC) have emerged as important pharmacophores. To date,
five BCC drugs (including boronic acids and boroles) have been approved by the FDA for …

Unnatural helical peptidic foldamers have attracted considerable attention owing to their
unique folding behaviours, diverse artificial protein binding mechanisms, and promising …

The covalent boron–diol interaction enables elaborate design of boronic acid‐based
saccharide sensors. Over the last decade, this research topic has been well developed …

Different classes of foldamers, which are synthetic oligomers that adopt well-defined
conformations in solution, have been the subject of extensive studies devoted to the …

Herein, we demonstrate the use of α‐boryl aldehydes and acyl boronates in the synthesis of
aminoboronic acid derivatives. This work highlights the untapped potential of boron …

Computer-assisted study and design of non-natural peptidomimetics is increasingly
important in the development of novel constructs with widespread applicability. Among these …

Peptides containing β-amino acids are unique non-natural polymers known to assemble into
protein-like tertiary and quaternary structures. When composed solely of β-amino acids, the …

Four novel bis-boronic acid compounds were synthesised via copper catalysed azide–
alkyne cycloaddition (CuAAC) reactions. Glucose selectivity was observed for a particular …

β3-peptides consisting exclusively of β3-amino acids adopt a variety of non-natural helical
structures and can self-assemble into well-defined hierarchical structures by axial head-to …