Removing extra CO2 in COPD patients

LW Lund, WJ Federspiel - Current respiratory care reports, 2013 - Springer
For patients experiencing acute respiratory failure due to a severe exacerbation of chronic
obstructive pulmonary disease (COPD), noninvasive positive pressure ventilation has been …

Current applications for the use of extracorporeal carbon dioxide removal in critically ill patients

L Camporota, N Barrett - BioMed research international, 2016 - Wiley Online Library
Mechanical ventilation in patients with respiratory failure has been associated with
secondary lung injury, termed ventilator‐induced lung injury. Extracorporeal venovenous …

Impact of membrane lung surface area and blood flow on extracorporeal CO2 removal during severe respiratory acidosis

C Karagiannidis, S Strassmann, D Brodie… - Intensive Care Medicine …, 2017 - Springer
Background Veno-venous extracorporeal CO 2 removal (vv-ECCO 2 R) is increasingly
being used in the setting of acute respiratory failure. Blood flow rates through the device …

Veno-venous extracorporeal CO2 removal for the treatment of severe respiratory acidosis: pathophysiological and technical considerations

C Karagiannidis, KA Kampe, FS Sipmann, A Larsson… - Critical care, 2014 - Springer
Introduction While non-invasive ventilation aimed at avoiding intubation has become the
modality of choice to treat mild to moderate acute respiratory acidosis, many severely …

Low respiratory rate plus minimally invasive extracorporeal Co2 removal decreases systemic and pulmonary inflammatory mediators in experimental acute respiratory …

S Grasso, T Stripoli, P Mazzone, M Pezzuto… - Critical Care …, 2014 - journals.lww.com
Objective: The Acute Respiratory Distress Syndrome Network protocol recommends limiting
tidal volume and plateau pressure; it also recommends increasing respiratory rate to prevent …

Impact of sweep gas flow on extracorporeal CO2 removal (ECCO2R)

S Strassmann, M Merten, S Schäfer, J de Moll… - Intensive Care Medicine …, 2019 - Springer
Background Veno-venous extracorporeal carbon dioxide (CO 2) removal (vv-ECCO 2 R) is
increasingly being used in the setting of acute respiratory failure. Blood flow rates range in …

Acidic sweep gas with carbonic anhydrase coated hollow fiber membranes synergistically accelerates CO2 removal from blood

DT Arazawa, JD Kimmel, MC Finn, WJ Federspiel - Acta biomaterialia, 2015 - Elsevier
The use of extracorporeal carbon dioxide removal (ECCO 2 R) is well established as a
therapy for patients suffering from acute respiratory failure. Development of next generation …

A novel pump-driven veno-venous gas exchange system during extracorporeal CO2-removal

A Hermann, K Riss, P Schellongowski, A Bojic… - Intensive care …, 2015 - Springer
Purpose Pump-driven veno-venous extracorporeal CO 2-removal (ECCO 2-R) increasingly
takes root in hypercapnic lung failure to minimize ventilation invasiveness or to avoid …

Avoidance of intubation during acute exacerbation of chronic obstructive pulmonary disease for a lung transplant candidate using extracorporeal carbon dioxide …

F Bonin, U Sommerwerck, LW Lund… - The Journal of thoracic and …, 2013 - jtcvs.org
For patients with severe chronic obstructive pulmonary disease (COPD) experiencing an
acute exacerbation, the necessity for invasive mechanical ventilation (IMV) not only is …

Carbonic anhydrase immobilized on hollow fiber membranes using glutaraldehyde activated chitosan for artificial lung applications

JD Kimmel, DT Arazawa, SH Ye… - Journal of Materials …, 2013 - Springer
Extracorporeal CO 2 removal from circulating blood is a promising therapeutic modality for
the treatment of acute respiratory failure. The enzyme carbonic anhydrase accelerates CO 2 …