Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

The retromer complex is a vital element of the endosomal protein sorting machinery that is
conserved across all eukaryotes. Retromer is most closely associated with the endosome-to …

Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids
between the different compartments of eukaryotic cells. They act by recruiting and/or …

Most functions of eukaryotic cells are controlled by cellular membranes, which are not static
entities but undergo frequent budding, fission, fusion, and sculpting reactions collectively …

Emerging findings disclose unexpected components of G protein-coupled receptor (GPCR)
signaling and cell biology. Select GPCRs exhibit classical signaling, that is restricted to cell …

The endosomal system is expansive and complex, characterized by swift morphological
transitions, dynamic remodeling of membrane constituents, and intracellular positioning …

Endosomes are dynamic intracellular compartments that control the sorting of a constant
stream of different transmembrane cargos either for ESCRT‐mediated degradation or for …

Retromer is a multi-protein complex that recycles transmembrane cargo from endosomes to
the trans-Golgi network and the plasma membrane. Defects in retromer impair various …

Phosphoinositides (PI s) form a minor class of phospholipids with crucial functions in cell
physiology, ranging from cell signalling and motility to a role as signposts of compartmental …

The N‐methyl‐D‐aspartate receptors (NMDARs) are ionotropic glutamate receptors that
mediate the flux of calcium (Ca2+) into the post‐synaptic compartment. Ca2+ influx …