Vitamin D: nutrient, hormone, and immunomodulator

F Sassi, C Tamone, P D'Amelio - Nutrients, 2018 - mdpi.com
The classical functions of vitamin D are to regulate calcium-phosphorus homeostasis and
control bone metabolism. However, vitamin D deficiency has been reported in several …

Vitamin D in autoimmunity: molecular mechanisms and therapeutic potential

W Dankers, EM Colin, JP Van Hamburg… - Frontiers in …, 2017 - frontiersin.org
Over the last three decades, it has become clear that the role of vitamin D goes beyond the
regulation of calcium homeostasis and bone health. An important extraskeletal effect of …

Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of …

G Saggese, F Vierucci, F Prodam, F Cardinale… - Italian journal of …, 2018 - Springer
Vitamin D plays a pivotal role in the regulation of calcium-phosphorus metabolism,
particularly during pediatric age when nutritional rickets and impaired bone mass acquisition …

Regulation of immune function by vitamin D and its use in diseases of immunity

AS Vanherwegen, C Gysemans… - … and Metabolism Clinics, 2017 - endo.theclinics.com
The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …

Autoimmune disease and interconnections with vitamin D

J Fletcher, EL Bishop, SR Harrison… - Endocrine …, 2022 - ec.bioscientifica.com
Vitamin D has well-documented effects on calcium homeostasis and bone metabolism but
recent studies suggest a much broader role for this secosteroid in human health. Key …

Pathophysiological role and therapeutic implications of vitamin D in autoimmunity: focus on chronic autoimmune diseases

M Bellan, L Andreoli, C Mele, PP Sainaghi… - Nutrients, 2020 - mdpi.com
Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology.
Besides the canonical regulatory activity on bone metabolism, several non-classical actions …

Vitamin D supplementation, glycemic control, and insulin resistance in prediabetics: a meta-analysis

N Mirhosseini, H Vatanparast, M Mazidi… - Journal of the …, 2018 - academic.oup.com
Diabetes prevention is a public health priority. Vitamin D supplementation may help prevent
the development of diabetes in persons at increased risk. We performed a meta-analysis of …

The role of vitamin D in diabetes and cardiovascular disease: an updated review of the literature

D Papandreou, ZTN Hamid - Disease markers, 2015 - Wiley Online Library
The dietary reference values for Vitamin D were set primarily considering its role in bone
health, but with the discovery of Vitamin D receptors throughout body tissues, new links with …

Vitamin D deficiency and glycemic status in children and adolescents with type 1 diabetes mellitus

S Savastio, F Cadario, G Genoni, G Bellomo… - PloS one, 2016 - journals.plos.org
Background Vitamin D (25OHD) effects on glycemic control are unclear in children and
adolescents with type 1 diabetes. Aims of this study were to investigate 25OHD status …

Determinants of vitamin D status in young adults: influence of lifestyle, sociodemographic and anthropometric factors

R Tønnesen, PH Hovind, LT Jensen, P Schwarz - BMC public health, 2016 - Springer
Background Very few studies have investigated the determinants of circulating 25-
hydroxyvitamin D (25 [OH] D) in young adults (18–25 years old) using a set of variables that …