Metabolic diseases including type 2 diabetes are associated with meta-inflammation. β-Cell
failure is a major component of the pathogenesis of type 2 diabetes. It is now well …

We review the current knowledge of pancreas pathology in type 1 diabetes. During the last
two decades, dedicated efforts toward the recovery of pancreas from deceased patients with …

Type 1 diabetes is an autoimmune disease initiated by the invasion of pancreatic islets by
immune cells that selectively kill the β cells. We found that rodent and human T lymphocytes …

One of the concepts explaining the coincidence of obesity and type 2 diabetes (T2D) is the
metaflammation theory. This chronic, low-grade inflammatory state originating from …

Type 1 diabetes is increasing in incidence in many parts of the world and it might be
imagined that the pathological processes that underlie disease progression are firmly …

Type 1 diabetes is caused by a deficiency of insulin secretion which has been considered
traditionally as the outcome of a precipitous decline in the viability of β-cells in the islets of …

The current review is informed about the effectiveness of plant-derived functional
components that aids in the regulation and health of endocrine glands. The endocrine …

Background Both types of diabetes are characterized by beta‐cell failure and death, leading
to insulin insufficiency. Very limited information is currently available about the ultrastructural …

Macrophages play a dynamic role in tissue repair following injury. Here we found that
following streptozotocin (STZ)-induced beta-cell death, mouse islet macrophages had …

Multiple and complex aetiological processes underlie diabetes mellitus, which invariably
result in the development of hyperglycaemia. Although there are two prevalent distinct forms …