[HTML][HTML] The molecular athlete: exercise physiology from mechanisms to medals

R Furrer, JA Hawley, C Handschin - Physiological Reviews, 2023 - journals.physiology.org
Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

[HTML][HTML] Magnesium in man: implications for health and disease

JHF De Baaij, JGJ Hoenderop… - Physiological …, 2015 - journals.physiology.org
Abstract Magnesium (Mg 2+) is an essential ion to the human body, playing an instrumental
role in supporting and sustaining health and life. As the second most abundant intracellular …

Skeletal muscle: a brief review of structure and function

WR Frontera, J Ochala - Calcified tissue international, 2015 - Springer
Skeletal muscle is one of the most dynamic and plastic tissues of the human body. In
humans, skeletal muscle comprises approximately 40% of total body weight and contains 50 …

Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers

M Dos Santos, S Backer, B Saintpierre, B Izac… - Nature …, 2020 - nature.com
Skeletal muscle fibers are large syncytia but it is currently unknown whether gene
expression is coordinately regulated in their numerous nuclei. Here we show by snRNA-seq …

[PDF][PDF] Mechanisms modulating skeletal muscle phenotype

B Blaauw, S Schiaffino, C Reggiani - Compr Physiol, 2013 - researchgate.net
Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

Biomaterials in tendon and skeletal muscle tissue engineering: current trends and challenges

M Beldjilali-Labro, A Garcia Garcia, F Farhat, F Bedoui… - Materials, 2018 - mdpi.com
Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …

A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes

M Dos Santos, S Backer, F Auradé, MMK Wong… - Nature …, 2022 - nature.com
The contractile properties of adult myofibers are shaped by their Myosin heavy chain isoform
content. Here, we identify by snATAC-seq a 42 kb super-enhancer at the locus regrouping …

Functional impact of sarcopenia in respiratory muscles

JE Elliott, SM Greising, CB Mantilla, GC Sieck - Respiratory physiology & …, 2016 - Elsevier
The risk for respiratory complications and infections is substantially increased in old age,
which may be due, in part, to sarcopenia (aging-related weakness and atrophy) of the …

[HTML][HTML] Mechanical properties of respiratory muscles

GC Sieck, LF Ferreira, MB Reid… - Comprehensive …, 2013 - ncbi.nlm.nih.gov
Striated respiratory muscles are necessary for lung ventilation and to maintain the patency of
the upper airway. The basic structural and functional properties of respiratory muscles are …

Magnesium deficiency and cardiometabolic disease

R Fritzen, A Davies, M Veenhuizen, M Campbell… - Nutrients, 2023 - mdpi.com
Magnesium (Mg2+) has many physiological functions within the body. These include
important roles in maintaining cardiovascular functioning, where it contributes to the …