Pleiotropic effects of melatonin
D Mahmood - Drug research, 2019 - thieme-connect.com
Melatonin's pleiotropic actions begin from controlling day/night cycle and
hypothalamic/pituitary axes to, for example, vasomotor effects, immunomodulation, antilipid …
hypothalamic/pituitary axes to, for example, vasomotor effects, immunomodulation, antilipid …
The multiple functions of melatonin in regenerative medicine
Melatonin research has been experiencing hyper growth in the last two decades; this relates
to its numerous physiological functions including anti-inflammation, oncostasis, circadian …
to its numerous physiological functions including anti-inflammation, oncostasis, circadian …
Erythropoietin mitigated thioacetamide-induced renal injury via JAK2/STAT5 and AMPK pathway
The kidney flushes out toxic substances and metabolic waste products, and homeostasis is
maintained owing to the kidney efforts. Unfortunately, kidney disease is one of the illnesses …
maintained owing to the kidney efforts. Unfortunately, kidney disease is one of the illnesses …
Vitamin D3 and erythropoietin protect against renal ischemia-reperfusion injury via heat shock protein 70 and microRNA-21 expression
Kidney ischemia reperfusion (IR) contributes to the development of acute kidney injury. The
hypoxic conditions in ischemic damage lead to oxidative stress and apoptotic cell death. We …
hypoxic conditions in ischemic damage lead to oxidative stress and apoptotic cell death. We …
Effects of melatonin on protecting against lung injury
W Wang, J Gao - Experimental and Therapeutic …, 2021 - spandidos-publications.com
Abstract Melatonin (MT; N‑acetyl‑5‑methoxy‑tryptamine), which has multiple effects and
roles, is secreted from the pineal gland at night according to the daily rhythm. In addition to …
roles, is secreted from the pineal gland at night according to the daily rhythm. In addition to …
Protective effect of melatonin for renal ischemia-reperfusion injury: a systematic review and meta-analysis
R Dun, T Lan, J Tsai, J Mao, Y Shao, X Hu… - Frontiers in …, 2022 - frontiersin.org
Background: Renal ischemia-reperfusion (I/R) injury is one of the major causes related to
acute kidney damage. Melatonin has been shown as a powerful antioxidant, with many …
acute kidney damage. Melatonin has been shown as a powerful antioxidant, with many …
Protective effect of dapsone against renal ischemia-reperfusion injury in rat
S Nezamoleslami, M Sheibani… - …, 2020 - Taylor & Francis
Background: Ischemia/reperfusion can cause injury to tissues and compromise functionality
of organs due to inflammatory processes. Significantly, development of these effects in …
of organs due to inflammatory processes. Significantly, development of these effects in …
Co-treatment with Esculin and erythropoietin protects against renal ischemia–reperfusion injury via P2X7 receptor inhibition and PI3K/Akt activation
Renal ischemia/reperfusion (RI/R) is a critical clinical outcome with slightly reported
improvement in mortality and morbidity. Effective therapies are still crucially required …
improvement in mortality and morbidity. Effective therapies are still crucially required …
Synergistic effects of N-acetylcysteine and mesenchymal stem cell in a lipopolysaccharide-induced interstitial cystitis rat model
JH Shin, CM Ryu, H Ju, HY Yu, S Song, DM Shin… - Cells, 2019 - mdpi.com
The purpose of this study was to reduce the amount of stem cells used in treating preclinical
interstitial cystitis (IC model) by investigating the synergistic effects of multipotent …
interstitial cystitis (IC model) by investigating the synergistic effects of multipotent …
Protective effect of ghrelin on testicular damages caused by chronic hypoxia in rats: a histopathological study
A Hazrati, R Salimnejad, MR Alipour… - Andrologia, 2018 - Wiley Online Library
Hypoxia can lead to changes in the blood flow, nutrition and oxygenation of male germ cells
and results in fertility reduction through the increase in oxidative stress. This study aims to …
and results in fertility reduction through the increase in oxidative stress. This study aims to …