Molecular mechanisms of brain-derived neurotrophic factor in neuro-protection: recent developments

H Zhao, A Alam, CY San, S Eguchi, Q Chen, Q Lian… - Brain research, 2017 - Elsevier
Neuronal cell injury, as a consequence of acute or chronic neurological trauma, is a
significant cause of mortality around the world. On a molecular level, the condition is …

C ell therapy for spinal cord injury with olfactory ensheathing glia cells (OEC s)

RM Gómez, MY Sánchez, M Portela‐Lomba, K Ghotme… - Glia, 2018 - Wiley Online Library
The prospects of achieving regeneration in the central nervous system (CNS) have
changed, as most recent findings indicate that several species, including humans, can …

Glial cell-axonal growth cone interactions in neurodevelopment and regeneration

MJ Rigby, TM Gomez, L Puglielli - Frontiers in neuroscience, 2020 - frontiersin.org
The developing nervous system is a complex yet organized system of neurons, glial support
cells, and extracellular matrix that arranges into an elegant, highly structured network. The …

Olfactory ensheathing cells for spinal cord injury: sniffing out the issues

R Yao, M Murtaza, JT Velasquez… - Cell …, 2018 - journals.sagepub.com
Olfactory ensheathing cells (OECs) are glia reported to sustain the continuous axon
extension and successful topographic targeting of the olfactory receptor neurons …

Olfactory ensheathing glia: their contribution to primary olfactory nervous system regeneration and their regenerative potential following transplantation into the injured …

EHP Franssen, FM de Bree, J Verhaagen - Brain research reviews, 2007 - Elsevier
Olfactory ensheathing glia (OEG) are a specialized type of glia that guide primary olfactory
axons from the neuroepithelium in the nasal cavity to the brain. The primary olfactory system …

Repair of neural pathways by olfactory ensheathing cells

G Raisman, Y Li - Nature Reviews Neuroscience, 2007 - nature.com
Damage to nerve fibre pathways results in a devastating loss of function, due to the
disconnection of nerve fibres from their targets. However, some recovery does occur and this …

Multi-target approaches to CNS repair: olfactory mucosa-derived cells and heparan sulfates

SL Lindsay, GA McCanney, AG Willison… - Nature Reviews …, 2020 - nature.com
Spinal cord injury (SCI) remains one of the biggest challenges in the development of
neuroregenerative therapeutics. Cell transplantation is one of numerous experimental …

Olfactory ensheathing cell transplantation following spinal cord injury: hype or hope?

MW Richter, AJ Roskams - Experimental neurology, 2008 - Elsevier
Olfactory ensheathing cells (OECs) are unique glia found only in the olfactory system that
retain exceptional plasticity, and support olfactory neurogenesis and the re-targeting across …

SPARC from olfactory ensheathing cells stimulates Schwann cells to promote neurite outgrowth and enhances spinal cord repair

E Au, MW Richter, AJ Vincent, W Tetzlaff… - Journal of …, 2007 - Soc Neuroscience
Olfactory ensheathing cells (OECs) transplanted into the lesioned CNS can stimulate
reportedly different degrees of regeneration, remyelination, and functional recovery, but little …

Phagocytosis by peripheral glia: Importance for nervous system functions and implications in injury and disease

L Nazareth, J St John, M Murtaza… - Frontiers in Cell and …, 2021 - frontiersin.org
The central nervous system (CNS) has very limited capacity to regenerate after traumatic
injury or disease. In contrast, the peripheral nervous system (PNS) has far greater capacity …