Vascular cognitive impairment

WM Van Der Flier, I Skoog, JA Schneider… - Nature Reviews …, 2018 - nature.com
The term vascular cognitive impairment (VCI) was introduced around the start of the new
millennium and refers to the contribution of vascular pathology to any severity of cognitive …

[HTML][HTML] Vascular cognitive impairment (VCI)

T Rundek, M Tolea, T Ariko, EA Fagerli, CJ Camargo - Neurotherapeutics, 2023 - Elsevier
Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

Impact of multiple pathologies on the threshold for clinically overt dementia

A Kapasi, C DeCarli, JA Schneider - Acta neuropathologica, 2017 - Springer
Longitudinal clinical–pathological studies have increasingly recognized the importance of
mixed pathologies (the coexistence of one or more neurodegenerative and cerebrovascular …

The pathology and pathophysiology of vascular dementia

RN Kalaria - Neuropharmacology, 2018 - Elsevier
Vascular dementia (VaD) is widely recognised as the second most common type of
dementia. Consensus and accurate diagnosis of clinically suspected VaD relies on wide …

Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study

OA Skrobot, SE Black, C Chen, C DeCarli… - Alzheimer's & …, 2018 - Wiley Online Library
Introduction Progress in understanding and management of vascular cognitive impairment
(VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple …

[HTML][HTML] Cerebral small vessel disease and vascular cognitive impairment: from diagnosis to management

MCZ Zotin, L Sveikata, A Viswanathan… - Current Opinion in …, 2021 - ncbi.nlm.nih.gov
SVD is the leading cause of VCI and is associated with substantial morbidity. Tackling
cardiovascular risk factors is currently the most effective approach to prevent cognitive …

Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease

Y Inoue, F Shue, G Bu, T Kanekiyo - Molecular neurodegeneration, 2023 - Springer
Vascular cognitive impairment and dementia (VCID) is commonly caused by vascular
injuries in cerebral large and small vessels and is a key driver of age-related cognitive …

Blood-brain barrier breakdown, neuroinflammation, and cognitive decline in older adults

GL Bowman, L Dayon, R Kirkland, J Wojcik… - Alzheimer's & …, 2018 - Elsevier
Introduction Blood-brain barrier (BBB) breakdown is observed in older versus younger
adults and in late-onset Alzheimer's disease versus age-matched controls, but its causes …

Microbiota‐microglia connections in age‐related cognition decline

R Zhou, S Qian, WCS Cho, J Zhou, C Jin, Y Zhong… - Aging …, 2022 - Wiley Online Library
Aging is an inevitable process that all individuals experience, of which the extent differs
among individuals. It has been recognized as the risk factor of neurodegenerative diseases …

Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementia

F Llorens, P Hermann, A Villar-Piqué… - Nature …, 2020 - nature.com
The clinical diagnosis of vascular dementia (VaD) is based on imaging criteria, and specific
biochemical markers are not available. Here, we investigated the potential of cerebrospinal …