Nanoengineered approaches to improve the efficacy of targeted drug delivery for the treatment of malignancy: a comprehensive review

J Bag, S Banerjee, A De, S Manna, S Banerjee… - Future Journal of …, 2023 - Springer
Background The second leading cause of mortality in the world, behind cardiovascular
disorders, is cancer. The currently employed treatment options including radiotherapy …

Real-time detection of sorafenib in human serum samples: An evaluation study via electrochemical sensing probe fabricated with silver stannate

N Nataraj, HY Hsu, TW Chen, SM Chen… - Journal of the Taiwan …, 2023 - Elsevier
Background In this present work we are aiming to develop an Ag 2 SnO 3 based
electrochemical sensor for the detection of kinase inhibitor sorafenib (SRF). The detection of …

Anti-liver cancer effects and mechanisms and its application in nano DDS of polysaccharides: A review

Z Yan, HQ Chen - International Journal of Biological Macromolecules, 2024 - Elsevier
Liver cancer is the third leading cause of cancer death, with high incidence and poor
treatment effect. In recent years, polysaccharides have attracted more and more attention in …

Synthesis of N-acetylcysteine functionalized cholic acid based triarmed poly DL-Lactide and encapsulation of gold nanoparticles: Studies on the antimicrobial activity …

N Ezhumalai, M Nanthagopal, J Kasthuri… - International Journal of …, 2024 - Elsevier
Cholic acid based biodegradable reverse polymeric micelles have been widely utilized as
preclinically suitable drug delivery system for poorly water-soluble drugs. In this report, we …

Efficient ultrasound-mediated drug delivery to orthotopic liver tumors–Direct comparison of doxorubicin-loaded nanobubbles and microbubbles

P Nittayacharn, E Abenojar, MB Cooley… - Journal of Controlled …, 2024 - Elsevier
Liver metastasis is a major obstacle in treating aggressive cancers, and current therapeutic
options often prove insufficient. To overcome these challenges, there has been growing …

Biotinylated polyaminoacid-based nanoparticles for the targeted delivery of lenvatinib towards hepatocarcinoma

P Varvarà, SE Drago, E Esposito, M Campolo… - International Journal of …, 2024 - Elsevier
In this work, we describe the development of targeted polymeric nanoparticles loaded with
lenvatinib for the treatment of hepatocellular carcinoma (HCC). A synthetic brush copolymer …

Preclinical evaluation of dalbergin loaded PLGA-galactose-modified nanoparticles against hepatocellular carcinoma via inhibition of the AKT/NF-κB signaling pathway

AK Gautam, P Kumar, V Kumar, A Singh… - International …, 2024 - Elsevier
Prior research has shown the effectiveness of dalbergin (DL), dalbergin nanoformulation
(DLF), and dalbergin-loaded PLGA–galactose-modified nanoparticles (DLMF) in treating …

Upgraded theragnostic strategies of multivariate nano gold in the management of hepatocellular carcinoma

D Halder, A Gupta, S Chakraborty, P Roy… - Nano-Structures & Nano …, 2024 - Elsevier
Hepatocellular Carcinoma is one of the detrimental forms of liver cancer perceived to be the
fourth most dangerous disease on a global forum. The prevalence of HCC is increasing day …

Navigating Skin Delivery Horizon: An Innovative Approach in Pioneering Surface Modification of Ultradeformable Vesicles

D Nayak, M Rathnanand, VK Tippavajhala - AAPS PharmSciTech, 2024 - Springer
In the dynamic landscape of pharmaceutical advancements, the strategic application of
active pharmaceutical ingredients to the skin through topical and transdermal routes has …