The biological and clinical significance of emerging SARS-CoV-2 variants

K Tao, PL Tzou, J Nouhin, RK Gupta… - Nature Reviews …, 2021 - nature.com
The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

The global epidemic of the SARS-CoV-2 delta variant, key spike mutations and immune escape

D Tian, Y Sun, J Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
During the COVID-19 pandemic, SARS-CoV-2 variants have emerged and spread
worldwide. The Delta (B. 1.617. 2) variant was first reported in India in October 2020 and …

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B. 1.617. 2) variant in vaccinated and unvaccinated individuals in the UK: a prospective …

A Singanayagam, S Hakki, J Dunning… - The lancet infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant is highly transmissible
and spreading globally, including in populations with high vaccination rates. We aimed to …

Impact of circulating SARS-CoV-2 variants on mRNA vaccine-induced immunity

C Lucas, CBF Vogels, I Yildirim, JE Rothman, P Lu… - Nature, 2021 - nature.com
The emergence of SARS-CoV-2 variants with mutations in major neutralizing antibody-
binding sites can affect humoral immunity induced by infection or vaccination,,,,–. Here we …

Severity of Omicron (B. 1.1. 529) and Delta (B. 1.617. 2) SARS-CoV-2 infection among hospitalised adults: a prospective cohort study in Bristol, United Kingdom

C Hyams, R Challen, R Marlow, J Nguyen… - The Lancet Regional …, 2023 - thelancet.com
Background There is an urgent public health need to evaluate disease severity in adults
hospitalised with Delta and Omicron SARS-CoV-2 variant infections. However, limited data …

Comparative transmissibility of SARS-CoV-2 variants delta and alpha in New England, USA

R Earnest, R Uddin, N Matluk, N Renzette… - Cell Reports …, 2022 - cell.com
Summary The SARS-CoV-2 Delta variant rose to dominance in mid-2021, likely propelled by
an estimated 40%–80% increased transmissibility over Alpha. To investigate if this …

The global epidemic of SARS‐CoV‐2 variants and their mutational immune escape

D Tian, YH Sun, JM Zhou, Q Ye - Journal of medical virology, 2022 - Wiley Online Library
During the COVID‐19 pandemic, genetic variants of SARS‐CoV‐2 have been emerging and
spreading around the world. Several SARS‐CoV‐2 endemic variants were found in United …

Context-specific emergence and growth of the SARS-CoV-2 Delta variant

JT McCrone, V Hill, S Bajaj, RE Pena, BC Lambert… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Delta (Pango lineage B. 1.617. 2) variant of concern spread
globally, causing resurgences of COVID-19 worldwide,. The emergence of the Delta variant …

Possible future waves of SARS-CoV-2 infection generated by variants of concern with a range of characteristics

L Dyson, EM Hill, S Moore, J Curran-Sebastian… - Nature …, 2021 - nature.com
Viral reproduction of SARS-CoV-2 provides opportunities for the acquisition of
advantageous mutations, altering viral transmissibility, disease severity, and/or allowing …

[HTML][HTML] Delta variant: the new challenge of COVID-19 pandemic, an overview of epidemiological, clinical, and immune characteristics

R Rashedi, N Samieefar, M Akhlaghdoust… - Acta Bio Medica …, 2022 - ncbi.nlm.nih.gov
The SARS-CoV-2 genome has undergone several mutations since the beginning of the
pandemic in December 2019. A number of these mutants were associated with higher …