Recent advances in non-small cell lung cancer targeted therapy; an update review

M Araghi, R Mannani, A Heidarnejad maleki… - Cancer Cell …, 2023 - Springer
Lung cancer continues to be the leading cause of cancer-related death worldwide. In the last
decade, significant advancements in the diagnosis and treatment of lung cancer, particularly …

Lung adenocarcinoma tumor origin: a guide for personalized medicine

L Seguin, M Durandy, CC Feral - Cancers, 2022 - mdpi.com
Simple Summary Lung cancer is the leading cause of cancer-related death worldwide, with
an average 5-year survival rate of approximately 15%. Among the multiple histological type …

Genetic markers in lung cancer diagnosis: a review

K Wadowska, I Bil-Lula, Ł Trembecki… - International journal of …, 2020 - mdpi.com
Lung cancer is the most often diagnosed cancer in the world and the most frequent cause of
cancer death. The prognosis for lung cancer is relatively poor and 75% of patients are …

Current landscape of therapeutic resistance in lung cancer and promising strategies to overcome resistance

A Ashrafi, Z Akter, P Modareszadeh, P Modareszadeh… - Cancers, 2022 - mdpi.com
Simple Summary Despite an initial response to therapy, many lung cancer patients
inevitably develop resistance to therapy leading to decreased duration of response and …

Current status of immunotherapy for non-small cell lung cancer

T Yang, Y Xiong, Y Zeng, Y Wang, J Zeng… - Frontiers in …, 2022 - frontiersin.org
Nowadays, lung cancer is still the deadliest oncological disease in the world. Among them,
non-small cell lung cancer (NSCLC) accounts for 80%∼ 85% of all lung cancers, and its 5 …

[HTML][HTML] Pathomic features reveal immune and molecular evolution from lung preneoplasia to invasive adenocarcinoma

P Chen, FR Rojas, X Hu, A Serrano, B Zhu, H Chen… - Modern Pathology, 2023 - Elsevier
Recent statistics on lung cancer, including the steady decline of advanced diseases and the
dramatically increasing detection of early-stage diseases and indeterminate pulmonary …

[HTML][HTML] LINC01140 promotes the progression and tumor immune escape in lung cancer by sponging multiple microRNAs

R Xia, G Geng, X Yu, Z Xu, J Guo, H Liu… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Long intergenic non-protein coding RNA 1140 (LINC01140), a long non-coding
RNA, is highly expressed in various cancers; however, its biological functions in lung cancer …

Enlightening the path to NSCLC biomarkers: Utilizing the power of XAI-guided deep learning

K Dwivedi, A Rajpal, S Rajpal, V Kumar… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective The early diagnosis of Non-small cell lung cancer
(NSCLC) is of prime importance to improve the patient's survivability and quality of life …

Predicting lung adenocarcinoma prognosis, immune escape, and pharmacomic profile from arginine and proline-related genes

Z Wang, J Zhang, S Shi, H Ma, D Wang, C Zuo… - Scientific Reports, 2023 - nature.com
Lung adenocarcinoma (LUAD) is a highly heterogeneous disease that ranks first in
morbidity and mortality. Abnormal arginine metabolism is associated with inflammatory lung …

Smoking-related dysregulation of plasma circulating microRNAs: the Rotterdam study

I Karabegović, SCE Maas, Y Shuai, MA Ikram… - Human Genomics, 2023 - Springer
Background MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression.
Differential miRNA expression, which is widely shown to be associated with the …