5-Ene-4-thiazolidinones–An efficient tool in medicinal chemistry

D Kaminskyy, A Kryshchyshyn, R Lesyk - European journal of medicinal …, 2017 - Elsevier
The presented review is an attempt to summarize a huge volume of data on 5-ene-4-
thiazolidinones being a widely studied class of small molecules used in modern organic and …

Application of optical methods for determination of concentration of doxorubicin in blood and plasma

T Sikora, K Morawska, W Lisowski, P Rytel, A Dylong - Pharmaceuticals, 2022 - mdpi.com
The aim of presented research is to develop a simple and quick method of
spectrophotometric detection for the determination of doxorubicin hydrochloride in blood …

Theoretical and spectroscopic studies of a tricyclic antidepressant, imipramine hydrochloride

SG Sagdinc, C Azkeskin, A Eşme - Journal of Molecular Structure, 2018 - Elsevier
Abstract Imipramine hydrochloride ([H-IMI] Cl), C 19 H 24 N 2. HCl, is the prototypic tricyclic
antidepressant (TCA) inhibitor of norepinephrine and serotonin neuronal reuptake. The …

Molecular hybrids based on Pyrazole and 4-Thiazolidinone cores: Synthesis, characterization, and anticancer studies

M Mushtaque, MMA Rizvi - Journal of Molecular Structure, 2023 - Elsevier
A series of hybrid compounds (11a–d) bearing pyrazole (6a–d) and 4-thiazolidinone (10)
cores were synthesized and characterized. The molecular structure of the compounds was …

Synthesis of new pyridine-thiazolidin-4-one and pyridine-pyrazole-thiazolidin-4-one conjugates: Molecular modelling and docking as antimicrobial agents

HM Abumelha, OM Alatawi, AH Alessa… - Journal of Molecular …, 2024 - Elsevier
A series of new functionalized pyridine-thiazolidin-4-one and pyridine-pyrazole-thiazolidin-4-
one conjugates was synthesized. The DFT/B3LYP approach revealed that the synthesized …

New Nanosized Systems Doxorubicin—Amphiphilic Copolymers of N-Vinylpyrrolidone and (Di)methacrylates with Antitumor Activity

SV Kurmaz, VM Ignatiev, NS Emel'yanova, VA Kurmaz… - Pharmaceutics, 2022 - mdpi.com
Nanosized systems of DOX with antitumor activity on the base of micelle-like particles of
amphiphilic thermosensitive copolymers of N-vinylpyrrolidone (VP) with triethylene glycol …

Synthesis, molecular structure, quantum mechanical studies and urease inhibition assay of two new isatin derived sulfonylhydrazides

M Arshad, M Jadoon, Z Iqbal, M Fatima, M Ali… - Journal of molecular …, 2017 - Elsevier
Two new isatin derivatives (E)-N′-(1-allyl-2-oxoindolin-3-ylidene)-4-methylbenzenesulfono-
hydrazide (5) and (E)-N′-(1-allyl-2-oxoindolin-3-ylidene)-4-chlorobenzenesulfono …

Synthesis, Characterization, Molecular Docking, and Anticancer Evaluation of 4‐Thiazolidinone Analogues

M Mushtaque, F Avecilla, ZB Hafeez… - Journal of Heterocyclic …, 2019 - Wiley Online Library
Scaffolds containing one or more heteroatoms are ubiquitous in nature and are responsible
for almost every biological processes in flora and fauna. The fact that heterocyclic cores …

Synthesis, characterization, solubilization, cytotoxicity and antioxidant activity of aminomethylated dihydroquercetin

J Li, J Dong, J Ouyang, J Cui, Y Chen, F Wang… - …, 2017 - pubs.rsc.org
A dihydroquercetin derivative (DHQA) was prepared through aminomethylation to overcome
the low water solubility and bioavailability of dihydroquercetin (DHQ). DHQA was …

An Experimental and theoretical study of the conformational stability of triazinone fleximers: quantitative analysis for intermolecular interactions

A Kumar, P Singh, R Kumar, P Yadav… - …, 2023 - Wiley Online Library
Synthesis and characterization of triazinone based propylene linked phthalimide and
benzimidazole have been carried out for conformational analysis and the study of their …