Protein corona: a new approach for nanomedicine design
After administration of nanoparticle (NP) into biological fluids, an NP–protein complex is
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
formed, which represents the “true identity” of NP in our body. Hence, protein–NP interaction …
[HTML][HTML] Get out or die trying: Peptide-and protein-based endosomal escape of RNA therapeutics
RNA therapeutics offer great potential to transform the biomedical landscape, encompassing
the treatment of hereditary conditions and the development of better vaccines. However, the …
the treatment of hereditary conditions and the development of better vaccines. However, the …
Understanding the lipid and protein corona formation on different sized polymeric nanoparticles
T Lima, K Bernfur, M Vilanova, T Cedervall - Scientific reports, 2020 - nature.com
When in contact with biological fluids, nanoparticles dynamically absorb biomolecules like
proteins and lipids onto their surface, forming a “corona”. This biocorona is a dynamic and …
proteins and lipids onto their surface, forming a “corona”. This biocorona is a dynamic and …
The influence of nanoparticle shape on protein corona formation
R Madathiparambil Visalakshan, LE González García… - Small, 2020 - Wiley Online Library
Nanoparticles have become an important utility in many areas of medical treatment such as
targeted drug and treatment delivery as well as imaging and diagnostics. These advances …
targeted drug and treatment delivery as well as imaging and diagnostics. These advances …
Polymer-coated magnetite nanoparticles for protein immobilization
K Mylkie, P Nowak, P Rybczynski, M Ziegler-Borowska - Materials, 2021 - mdpi.com
Since their discovery, magnetic nanoparticles (MNPs) have become materials with great
potential, especially considering the applications of biomedical sciences. A series of works …
potential, especially considering the applications of biomedical sciences. A series of works …
The impact of protein corona on the biological behavior of targeting nanomedicines
For successful translation of targeting nanomedicines from bench to bedside, it is vital to
address their most common drawbacks namely rapid clearance and off-target accumulation …
address their most common drawbacks namely rapid clearance and off-target accumulation …
The interaction between nanoparticles-protein corona complex and cells and its toxic effect on cells
N Liu, M Tang, J Ding - Chemosphere, 2020 - Elsevier
Once nanoparticles (NPs) contact with the biological fluids, the proteins immediately adsorb
onto their surface, forming a layer called protein corona (PC), which bestows the biological …
onto their surface, forming a layer called protein corona (PC), which bestows the biological …
Effect of nanoparticle size and PEGylation on the protein corona of PLGA nanoparticles
K Partikel, R Korte, NC Stein, D Mulac… - European Journal of …, 2019 - Elsevier
Upon intravenous administration of nanoparticles (NP) into the bloodstream, proteins bind
rapidly on their surface resulting in a formation of a so-called 'Protein Corona'. These …
rapidly on their surface resulting in a formation of a so-called 'Protein Corona'. These …
Artificial engineering of the protein corona at bio-nano interfaces for improved cancer-targeted nanotherapy
Nanoparticles (NPs) have been used in numerous applications as anticancer, antibacterial
and antioxidant agents. Artificial engineering of protein interactions with NPs in biological …
and antioxidant agents. Artificial engineering of protein interactions with NPs in biological …
Protein corona formation on lipid nanoparticles negatively affects the NLRP3 inflammasome activation
The interaction between lipid nanoparticles (LNPs) and serum proteins, giving rise to a
unique identification in the form of the protein corona, has been shown to be associated with …
unique identification in the form of the protein corona, has been shown to be associated with …